De Vries Nutrition Solutions Inc., 7213 CE Gorssel, The Netherlands.
R & D Department, Tereos, Rue de Senlis, 77230 Moussy-Le-Vieux, France.
Nutrients. 2019 Jan 4;11(1):91. doi: 10.3390/nu11010091.
The aim of this systematic review and meta-analysis was to assess the effects of β-fructan supplementation on bowel function in healthy volunteers and patients. The search process was based on the selection of publications listed in the Pubmed and EUPMC database until December 2017, plus two unpublished studies, to identify studies evaluating the impact of β-fructans on bowel movement and stool parameters. Forty-seven publications were selected for inclusion. Primary parameter was frequency of bowel movements, evaluated by the number of defecations per day during the study period. Secondary outcomes were stool consistency, stool dry and wet weights, and transit time. Short-chain (DP < 10) β-fructans contributed to increased stool frequency (0.36 defecation +/- 0.06 per day; < 0.001), while no significant effect was reported with long-chain (DP ≥ 10) β-fructans (-0.03 +/- 0.11, = 0.82). A minimal increase in stool wet weight was also statistically demonstrated with short-chain β-fructans. Moreover, the meta-analysis highlighted significant differences in stool consistency in contrast to fecal dry weight after β-fructan supplementation. This systematic review and meta-analysis indicates that short-chain β-fructan supplementation has a positive effect on bowel function by significantly increasing the frequency of bowel movements.
本系统评价和荟萃分析的目的是评估 β-果聚糖补充剂对健康志愿者和患者肠道功能的影响。搜索过程基于对 Pubmed 和 EUPMC 数据库中列出的出版物的选择，直到 2017 年 12 月，加上两项未发表的研究，以确定评估 β-果聚糖对肠道运动和粪便参数影响的研究。选择了 47 篇出版物进行纳入。主要参数是通过研究期间每天的排便次数评估的排便频率。次要结局是粪便稠度、粪便干湿重和转运时间。短链（DP < 10）β-果聚糖有助于增加粪便频率（每天 0.36 次排便 +/- 0.06； < 0.001），而长链（DP ≥ 10）β-果聚糖则没有明显的效果（-0.03 +/- 0.11， = 0.82）。短链 β-果聚糖也在统计学上显示出粪便湿重的轻微增加。此外，荟萃分析强调了 β-果聚糖补充后粪便稠度与粪便干重之间的显著差异。本系统评价和荟萃分析表明，短链 β-果聚糖补充剂通过显著增加排便频率对肠道功能有积极影响。
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