Meignan F, Falcot J, Carret J L, Thierry J
Services de Médecine B et biologie médicale H. I. A. Desgenettes, Lyon.
Bull Soc Pathol Exot Filiales. 1987;80(3 Pt 2):443-6.
The existence of Plasmodium falciparum chloroquine-resisting clones in equatorial Africa is quite a recent event. Among a French military unit of 138 people who had lived in Gabon from April to August 1986, 24 of them have caught malaria due to Plasmodium falciparum. This allows us to perceive the impact of this event because of the perfect control of chloroquine prophylaxis and the good knowledge of all the attacks of fever which occurred in the field. Admitting 10 of those people into the department of internal medicine of the Military Hospital Desgenettes located in Lyons, we could have seen that trophozoites of Plasmodium falciparum were still persisting 2 months after their return for 8 of them in spite of carrying on chemoprophylaxis. Observing that in the field, sets the problem of the chemoprophylaxis of malaria for the troops maneuvering in chloroquine-resisting areas and warrants, if justified, a work protocol aimed at solving it.
赤道非洲存在恶性疟原虫氯喹抗性克隆是相当近期的事件。在1986年4月至8月期间居住在加蓬的一个138人的法国军事单位中，有24人感染了由恶性疟原虫引起的疟疾。由于氯喹预防措施的完美实施以及对该地区发生的所有发热发作的充分了解，这使我们能够认识到这一事件的影响。将其中10人收治到位于里昂的德热内特军事医院内科，我们可以看到，尽管他们持续进行化学预防，但其中8人在返回后2个月，其恶性疟原虫滋养体仍持续存在。在实地观察到这一点，提出了在氯喹抗性地区行动的部队疟疾化学预防问题，并且如果有理由的话，需要一个旨在解决该问题的工作方案。
