Skin Therapy Lett. 2020 Nov;25(5):7-11.
Nicotinamide (or niacinamide), a form of vitamin B3 that is often confused with its precursor nicotinic acid (or niacin), is a low-cost, evidence-based oral treatment option for actinic keratosis, squamous cell carcinomas, basal cell carcinomas, and bullous pemphigoid. Despite its favorable safety profile and affordability, the integration of nicotinamide into clinical practice is an ongoing process, and like many over-the-counter supplements it has faced some barriers. The purpose of this article is to address some of those barriers by reviewing its efficacy, safety profile, and emphasizing the difference between nicotinamide and niacin. Lastly, we offer practical guidance around recommendations and the availability of nicotinamide, which can be hard to find for patients and providers alike.
烟酰胺（或烟酰胺），维生素 B3 的一种形式，常与前体烟酸（或烟碱）混淆，是一种低成本、基于证据的光化性角化病、鳞状细胞癌、基底细胞癌和大疱性类天疱疮的口服治疗选择。尽管其安全性良好且价格合理，但烟酰胺在临床实践中的整合仍在进行中，并且像许多非处方补充剂一样，它也面临一些障碍。本文的目的是通过回顾其疗效、安全性概况，并强调烟酰胺和烟酸之间的区别，来解决其中的一些障碍。最后，我们就烟酰胺的推荐和供应提供了实用的指导，这对患者和提供者来说都很难找到。
