Italian Agency for Development Cooperation, 33 Street, Amarat, Khartoum, Sudan.
Unit of Andrology and Reproductive Medicine, Department of Medicine, University of Padova, Padova, Italy.
Environ Sci Pollut Res Int. 2021 Jan;28(4):4095-4103. doi: 10.1007/s11356-020-11589-z. Epub 2020 Nov 16.
Male fertility and semen quality have declined over recent decades. Among other causes, exposure to environmental and occupational pollution has been linked to adverse reproductive outcomes, but effects on male semen quality are still uncertain. Therefore, the aim of the present study was to conduct a systematic review and meta-analysis to assess current evidence regarding the impact of exposure to tobacco smoke and environmental and occupational pollution on sperm quality in humans. In the meta-analysis, 22 studies are included showing that environmental and occupational pollutants may affect sperm count, volume, concentration, motility, vitality and sperm DNA, and chromatin integrity. All included articles reported significant alterations in at least one of the outcomes studied in association with at least one of the pollutants studied. Considering that sperm quality can be considered a proxy for general health and that pollutants have a dramatic impact on climate change, it would be strongly recommended to better understand the role of pollutants on human, animal, and planetary health.
近几十年来，男性生育力和精液质量有所下降。在其他原因中，环境和职业污染的暴露与不良生殖结局有关，但对男性精液质量的影响仍不确定。因此，本研究旨在进行系统评价和荟萃分析，以评估目前关于暴露于烟草烟雾以及环境和职业污染对人类精子质量影响的证据。在荟萃分析中，纳入了 22 项研究，表明环境和职业污染物可能会影响精子计数、体积、浓度、活力、生命力和精子 DNA 及染色质完整性。所有纳入的文章都报告了至少一项研究结果发生了显著变化，与至少一种研究污染物有关。考虑到精子质量可以被认为是一般健康的代表，而且污染物对气候变化有巨大影响，强烈建议更好地了解污染物对人类、动物和地球健康的作用。
