Van Stan Jarrad H, Mehta Daryush D, Ortiz Andrew J, Burns James A, Marks Katherine L, Toles Laura E, Stadelman-Cohen Tara, Krusemark Carol, Muise Jason, Hron Tiffiny, Zeitels Steven M, Fox Annie B, Hillman Robert E
Massachusetts General Hospital, Boston.
Harvard Medical School, Boston, MA.
J Speech Lang Hear Res. 2020 Dec 14;63(12):3934-3944. doi: 10.1044/2020_JSLHR-20-00168. Epub 2020 Nov 16.
Purpose This study attempts to gain insights into the role of daily voice use in the etiology and pathophysiology of phonotraumatic vocal hyperfunction (PVH) by applying a logistic regression-based daily phonotrauma index (DPI) to predict group-based improvements in patients with PVH after laryngeal surgery and/or postsurgical voice therapy. Method A custom-designed ambulatory voice monitor was used to collect 1 week of pre- and postsurgery data from 27 female patients with PVH; 13 of these patients were also monitored after postsurgical voice therapy. Normative weeklong data were obtained from 27 matched controls. Each week was represented by the DPI, standard deviation of the difference between the first and second harmonic amplitudes (H1-H2). Results Compared to pretreatment, the DPI significantly decreased in the patient group after surgery (Cohen's effect size = -0.86) and voice therapy ( = -1.06). The patient group DPI only normalized after voice therapy. Conclusions The DPI produced the expected pattern of improved ambulatory voice use across laryngeal surgery and postsurgical voice therapy in a group of patients with PVH. The results were interpreted as providing new objective information about the role of daily voice use in the etiology and pathophysiology of PVH. The DPI is viewed as an estimate of potential vocal fold trauma that relies on combining the long-term distributional characteristics of two parameters representing the magnitude of phonatory forces (neck-surface acceleration magnitude) and vocal fold closure dynamics (H1-H2). Further validation of the DPI is needed to better understand its potential clinical use.
目的 本研究试图通过应用基于逻辑回归的每日发声创伤指数(DPI)来深入了解日常发声在发声创伤性嗓音功能亢进(PVH)的病因学和病理生理学中的作用,以预测喉手术后和/或术后嗓音治疗后PVH患者基于组别的改善情况。方法 使用定制设计的动态嗓音监测仪收集27例女性PVH患者手术前后1周的数据;其中13例患者在术后嗓音治疗后也进行了监测。从27名匹配的对照者中获取了为期一周的标准数据。每周的数据用DPI表示,即基频与第一谐波振幅之差的标准差(H1-H2)。结果 与治疗前相比,患者组在手术后(科恩效应量=-0.86)和嗓音治疗后(=-1.06)DPI显著降低。患者组的DPI仅在嗓音治疗后恢复正常。结论 DPI在一组PVH患者中呈现出预期的模式,即通过喉手术和术后嗓音治疗改善了动态发声情况。这些结果被解释为提供了关于日常发声在PVH病因学和病理生理学中作用的新的客观信息。DPI被视为对潜在声带创伤的一种估计,它依赖于结合两个参数的长期分布特征,这两个参数分别代表发声力的大小(颈部表面加速度大小)和声带闭合动态(H1-H2)。需要对DPI进行进一步验证,以更好地了解其潜在的临床应用。