Department of Physiotherapy, University of Sevilla, 41009 Seville, Spain.
Department of Physiotherapy, Faculty of Nursing, Physiotherapy and Podiatry, University of Seville, C/Avicena s/n, 41009 Seville, Spain.
Int J Environ Res Public Health. 2020 Nov 12;17(22):8382. doi: 10.3390/ijerph17228382.
The primary purpose of this research was to investigate the feasibility and safety of delivering an early supervised physical therapy intervention to women after sentinel lymph node biopsy (SLNB); furthermore, we aimed to provide explorative data on its effects. This was a single-site feasibility study. Pre- and post-evaluation was conducted from baseline to follow-up at 6 months. Primary outcomes were participant recruitment, participant retention, compliance with the intervention, and safety. Secondary outcomes were shoulder range of motion, handgrip strength, upper limb pain and disability, scar recovery, quality of life, and the incidence of axillary web syndrome (AWS) and/or lymphoedema. A total of 43 participants (mean age 55.37 years) completed the trial and the follow-up period. A total of 91% of women who met the inclusion criteria agreed to participate, and the adherence rate was 80%. No adverse events were reported. Incidence of AWS was 9.3%, and there was no incidence of lymphoedema at 6 months. Our results support that this intervention is feasible and safe. The results presented in this study also provide preliminary evidence for the use of a rehabilitation program as a supportive intervention after SLNB, but future research on effectiveness is needed.
本研究的主要目的是探讨对前哨淋巴结活检（SLNB）后女性进行早期监督物理治疗干预的可行性和安全性；此外，我们旨在提供关于其效果的探索性数据。这是一项单站点可行性研究。从基线到 6 个月的随访进行了预评估和后评估。主要结局指标是参与者招募、参与者保留、干预依从性和安全性。次要结局指标是肩部活动范围、手握力、上肢疼痛和残疾、疤痕恢复、生活质量以及腋网综合征（AWS）和/或淋巴水肿的发生率。共有 43 名（平均年龄 55.37 岁）参与者完成了试验和随访期。符合纳入标准的女性中，有 91%同意参加，且依从率为 80%。未报告不良事件。AWS 的发生率为 9.3%，6 个月时无淋巴水肿发生。我们的结果支持该干预措施是可行和安全的。本研究的结果还提供了在 SLNB 后使用康复计划作为辅助干预的初步证据，但需要进一步研究其有效性。
