Division of Endocrinology, Internal Medicine, Tongji Hospital, Huazhong University of Science & Technology, Wuhan, China, 430030.
Department of Nuclear Medicine, Tongji Hospital, Huazhong University of Science & Technology, Wuhan, China, 430030.
Trends Endocrinol Metab. 2020 Dec;31(12):885-890. doi: 10.1016/j.tem.2020.10.003. Epub 2020 Nov 13.
Application of autologous platelet-rich plasma (PRP), especially leukocyte- and platelet-rich fibrin (L-PRF), has emerged as a promising adjuvant therapy for the treatment of diabetic foot ulcers (DFUs). Conflicting results of PRP efficacy can be attributed to the lack of standardization in the PRP preparation process in addition to a paucity of well-designed randomized clinic trials (RCTs).
富血小板血浆（PRP），尤其是富含白细胞和血小板的纤维蛋白（L-PRF）的应用，已成为治疗糖尿病足溃疡（DFUs）的一种很有前途的辅助治疗方法。PRP 疗效的结果相互矛盾，这归因于 PRP 制备过程缺乏标准化，以及缺乏精心设计的随机临床试验（RCT）。
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