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自体脂肪移植用于术后乳房重建：一项系统评价。

Autologous fat grafting for postoperative breast reconstruction: A systemic review.

作者信息

Yu Wenxin, Wang Zhenghui, Dai Yuhan, Zhao Shuhan, Chen Huilin, Wang Shui, Xie Hui

机构信息

Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.

出版信息

Regen Ther. 2024 Oct 30;26:1010-1017. doi: 10.1016/j.reth.2024.10.007. eCollection 2024 Jun.

DOI:10.1016/j.reth.2024.10.007
PMID:39553540
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11564784/
Abstract

Autologous fat grafting technology has become a new method for breast reconstruction after breast surgery due to its advantages of simple operation, low immunogenicity, fewer complications, high patient acceptance, and natural filling effect. However, the unpredictable fate of transplanted fat limits its widespread application. Currently, many studies have made certain progress in improving the survival rate of fat grafts. This article provides an overview of autologous fat grafting technology, including the mechanisms of fat graft survival, techniques for obtaining and transplanting adipose tissue, methods for enhancing graft survival, and complications associated with fat grafting.

摘要

自体脂肪移植技术因其操作简单、免疫原性低、并发症少、患者接受度高及填充效果自然等优点，已成为乳房手术后乳房重建的一种新方法。然而，移植脂肪不可预测的命运限制了其广泛应用。目前，许多研究在提高脂肪移植成活率方面取得了一定进展。本文综述了自体脂肪移植技术，包括脂肪移植存活的机制、获取和移植脂肪组织的技术、提高移植物存活的方法以及与脂肪移植相关的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ec1/11564784/9c44dea7c58f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ec1/11564784/9c44dea7c58f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ec1/11564784/9c44dea7c58f/gr1.jpg

相似文献

[1]
Autologous fat grafting for postoperative breast reconstruction: A systemic review.

Regen Ther. 2024-10-30

[2]
Oncologic Safety of Autologous Fat Grafting in Breast Reconstruction.

Clin Breast Cancer. 2021-8

[3]
[APPLICATION AND RESEARCH PROGRESS OF AUTOLOGOUS FAT GRAFTING IN BREAST RECONSTRUCTION].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2016-1

[4]
[Application of autologous fat grafting in breast reconstruction].

Zhonghua Wai Ke Za Zhi. 2017-9-1

[5]
Breast Reconstruction Using a Three-Dimensional Absorbable Mesh Scaffold and Autologous Fat Grafting: A Composite Strategy Based on Tissue-Engineering Principles.

Plast Reconstr Surg. 2020-10

[6]
Does Stromal Vascular Fraction Ensure a Higher Survival in Autologous Fat Grafting for Breast Augmentation? A Volumetric Study Using 3-Dimensional Laser Scanning.

Aesthet Surg J. 2019-1-1

[7]
[Research progress of external volume expansion assisted autologous fat grafting for breast reconstruction].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2022-3-15

[8]
The role of autologous fat grafting in secondary microsurgical breast reconstruction.

Ann Plast Surg. 2013-7

[9]
Autologous Fat Grafting After Breast Reconstruction in Postmastectomy Patients: Complications, Biopsy Rates, and Locoregional Cancer Recurrence Rates.

Ann Plast Surg. 2016-3

[10]
Oncological Safety of Autologous Fat Grafting in Breast Reconstruction: A Meta-analysis Based on Matched Cohort Studies.

Aesthetic Plast Surg. 2022-6

引用本文的文献

[1]
Maximizing the Longevity and Volume Retention of Fat Grafts: Advances in Clinical Practice.

Cureus. 2025-7-22

[2]
Large Fibrous Connective Tissue Reduces Oxidative Stress to Form a Living Cell Scaffold in Adipose Grafts.

Antioxidants (Basel). 2025-2-26

[3]
The Regenerative Marriage Between High-Density Platelet-Rich Plasma and Adipose Tissue.

Int J Mol Sci. 2025-2-27

本文引用的文献

[1]
Cancer statistics, 2024.

CA Cancer J Clin. 2024

[2]
Fat Grafting: Basic Science, Techniques, and Patient Management.

Plast Reconstr Surg Glob Open. 2022-3-18

[3]
Case Report and Literature Review: Catastrophic Embolism Following Cosmetic Injection of Autologous Fat in the Face.

Front Med (Lausanne). 2021-12-7

[4]
Effect of Intra-articular Platelet-Rich Plasma vs Placebo Injection on Pain and Medial Tibial Cartilage Volume in Patients With Knee Osteoarthritis: The RESTORE Randomized Clinical Trial.

JAMA. 2021-11-23

[5]
Long-Term Effects of Platelet-Rich Fibrin on Fat Graft Survival and Their Optimal Mixing Ratio.

Aesthet Surg J. 2021-6-14

[6]
Human adipose-derived stem cells enriched with VEGF-modified mRNA promote angiogenesis and long-term graft survival in a fat graft transplantation model.

Stem Cell Res Ther. 2020-11-19

[7]
Autologous Platelet-Rich Plasma for Diabetic Foot Ulcer.

Trends Endocrinol Metab. 2020-12

[8]
Cell-Assisted Lipotransfer for Cosmetic Breast Augmentation: Supportive Use of Adipose-Derived Stem/Stromal Cells.

Aesthetic Plast Surg. 2020-8

[9]
FGF2-induced PI3K/Akt signaling evokes greater proliferation and adipogenic differentiation of human adipose stem cells from breast than from abdomen or thigh.

Aging (Albany NY). 2020-7-24

[10]
The Impact of Lidocaine on Adipose-Derived Stem Cells in Human Adipose Tissue Harvested by Liposuction and Used for Lipotransfer.

Int J Mol Sci. 2020-4-20

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