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小肠胶囊内镜在哥伦比亚小肠疾病研究中的临床应用:国家注册研究结果。

Clinical utility of the small bowel capsule endoscopy in the study of small bowel diseases in Colombia: Results of a national registry.

机构信息

Hospital Pablo Tobón Uribe, Medellín, Colombia.

MTG Servimed SAS, Bogotá, Colombia.

出版信息

Gastroenterol Hepatol. 2021 May;44(5):346-354. doi: 10.1016/j.gastrohep.2020.09.011. Epub 2020 Oct 29.

Abstract

INTRODUCTION

The small bowel capsule endoscopy (SBCE) has revolutionised the study of small bowel diseases. The objective of this study is to determine the indications, findings and diagnostic yield of SBCE in a national registry.

PATIENTS AND METHODS

An observational, analytical cross-sectional study was carried out, analysing the SBCE records at seven centres in the country, where different variables were collected.

RESULTS

1,883 SBCEs were evaluated. The average age was 55.4 years (5.6-94.2). The most frequent indications were suspicion of small bowel bleeding (SBB) (64.4%), study of Crohn's disease (15.2%) and chronic diarrhoea (11.2%). 54.3% were prepared with laxatives. The most frequent lesions found were erosions/ulcers (31.6%), angioectasias (25.7%) and parasitosis (2.7%). The diagnostic yield (P1+P2, Saurin classification) of SBCE in SBB was 60.6%, being higher in overt SBB (66.0%) compared to occult SBB (56.0%) (P=.003). The studies with better preparation showed higher detection of lesions (93.8% vs. 89.4%) (OR=1.8, CI: 95%: 1.2-2.6; P=.004). The SBCE complication rate was 3.1%, with complete SB visualisation at 96.6% and SB retention rate of 0.7%. 81.5% of SBCEs were performed on an outpatient basis, and presented a greater complete SB visualisation than hospital ones (97.1% vs. 94.3%) (OR=2.1, CI: 95%, 1.2-3.5; P=.008).

CONCLUSIONS

The indications, findings and diagnostic performance of SBCEs in Colombia are similar to those reported in the literature, with a high percentage of complete studies and a low rate of complications.

摘要

简介

小肠胶囊内镜(SBCE)彻底改变了小肠疾病的研究方式。本研究的目的是在国家注册中心确定 SBCE 的适应证、发现和诊断率。

患者和方法

进行了一项观察性、分析性的横断面研究,分析了该国 7 个中心的 SBCE 记录,收集了不同的变量。

结果

共评估了 1883 例 SBCE。平均年龄为 55.4 岁(5.6-94.2)。最常见的适应证是疑似小肠出血(SBB)(64.4%)、克罗恩病(15.2%)和慢性腹泻(11.2%)。54.3%的患者用泻药准备。最常见的病变是糜烂/溃疡(31.6%)、血管扩张(25.7%)和寄生虫病(2.7%)。在 SBB 中,SBCE 的诊断率(P1+P2,Saurin 分类)为 60.6%,显性 SBB (66.0%)高于隐匿性 SBB (56.0%)(P=.003)。准备更好的研究显示出更高的病变检出率(93.8%比 89.4%)(OR=1.8,95%CI:1.2-2.6;P=.004)。SBCE 的并发症发生率为 3.1%,完全 SB 可视化率为 96.6%,SB 保留率为 0.7%。81.5%的 SBCE 在门诊进行,其完全 SB 可视化率高于住院患者(97.1%比 94.3%)(OR=2.1,95%CI:1.2-3.5;P=.008)。

结论

哥伦比亚的 SBCE 适应证、发现和诊断性能与文献报道相似,具有较高的完全研究比例和较低的并发症发生率。

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