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胶囊内镜对疑似小肠出血患者的临床影响:哥伦比亚一家专科医院的经验。

Clinical impact of capsule endoscopy on patients with suspected small bowel bleeding: Experience at a highly specialized hospital in Colombia.

机构信息

Departamento de Medicina Interna, Facultad de Ciencias de la Salud, Universidad Icesi, Cali, Valle del Cauca, Colombia.

Centro de Investigaciones Clínicas (CIC), Fundación Valle del Lili, Cali, Valle del Cauca, Colombia.

出版信息

Rev Gastroenterol Mex (Engl Ed). 2024 Apr-Jun;89(2):222-231. doi: 10.1016/j.rgmxen.2023.04.014. Epub 2023 Oct 11.

Abstract

INTRODUCTION AND AIMS

Capsule endoscopy is part of the diagnostic approach to patients with suspected small bowel bleeding and data on its clinical impact are still limited in developing countries. The primary aim of the present study was to determine its impact on subsequent diagnostic and therapeutic decisions.

MATERIAL AND METHODS

A retrospective study was conducted that included all the patients that underwent capsule endoscopy with the PillCam™ SB 3 Capsule system due to suspected small bowel bleeding treated at the Hospital Universitario Fundación Valle del Lili between January 2011 and December 2020.

RESULTS

A total of 158 patients met the inclusion criteria. Mean patient age was 63 years (interquartile range [IQR], 52-74), 53.6% of the patients were women, and high blood pressure was the most frequent comorbidity (43.7%). The main indication was overt bleeding (58.2%). Of all the capsule endoscopies carried out, 63.9% showed lesions that were potentially responsible for bleeding. Medical or surgical treatment was indicated in 63.3% of the case total. Rebleeding at 6 months occurred in 15 patients and there were 2 deaths due to gastrointestinal bleeding at 6 months.

CONCLUSIONS

Capsule endoscopy has a high impact on patients with suspected small bowel bleeding, with respect to clinical decision-making, as well as rebleeding, hospitalization, and mortality outcomes. The positivity rate of lesions potentially responsible for bleeding was similar to that reported in developed countries.

摘要

简介和目的

胶囊内镜检查是疑似小肠出血患者诊断方法的一部分,在发展中国家,其临床影响的数据仍有限。本研究的主要目的是确定其对后续诊断和治疗决策的影响。

材料和方法

本研究为回顾性研究,纳入了 2011 年 1 月至 2020 年 12 月在 Fundacion Valle del Lili 大学医院因疑似小肠出血接受 PillCam™ SB 3 胶囊系统胶囊内镜检查的所有患者。

结果

共有 158 名患者符合纳入标准。患者平均年龄为 63 岁(四分位间距 [IQR],52-74),53.6%为女性,最常见的合并症是高血压(43.7%)。主要指征是显性出血(58.2%)。在所有进行的胶囊内镜检查中,63.9%显示出可能导致出血的病变。总的来说,63.3%的病例需要进行药物或手术治疗。15 例患者在 6 个月时出现再出血,2 例患者在 6 个月时因胃肠道出血死亡。

结论

胶囊内镜检查对疑似小肠出血患者的临床决策具有重要影响,同时对再出血、住院和死亡率也有影响。潜在出血病变的阳性率与发达国家报道的相似。

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