Division of Endoscopy, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Acta Gastroenterol Belg. 2022 Jul-Sep;85(3):509-517. doi: 10.51821/85.3.10322. Epub 2022 Jun 30.
Small-bowel capsule endoscopy (SBCE) is a safe and efficient method for diagnosis of small-bowel diseases. Since its development, different models have appeared. The aim of this study was to analyze which of the different models of SBCE has the best diagnostic yield.
Extensive medical literature research was reviewed, using MESH terms, searching studies comparing different SBCE types. We analyzed the diagnostic yield of all the comparisons and when there were 2 or more studies that compared the same model of SBCEs, a meta-analysis was performed.
Ten eligible studies including 1065 SBCEs procedures were identified. The main indication was occult gastrointestinal bleeding in 9/10 studies. Two of them included anemia, chronic diarrhea and/or chronic abdominal pain. The indication in one article was celiac disease. In 9 studies, different types of SBCEs (MiroCam, Endocapsule, OMOM and CapsoCam) were compared with PillCam (SB, SB2 and SB3). Three studies compared MiroCam vs PillCam and CapsoCam vs PillCam, while two studies contrast Endocapsule vs PillCam. None of the SBCEs show superiority over PillCam [OR 0.78 (95%CI;0.60-1.01)]. One study compared SBCEs other than Pillcam (MiroCam vs Endocapsule). Nine studies did not find statistical differences between SBCEs, one showed better diagnostic yield of Mirocam compared with PillCam SB3 (p=0.02). The difference between these SBCE was not replayed in the metaanalysis [OR 0.77 (95%CI;0.49-1.21)].
Despite the appearance of new SBCE models, there are no differences in diagnostic yield; therefore, SBCE endoscopist's performance should be based on experience and availability.
小肠胶囊内镜（SBCE）是一种安全有效的诊断小肠疾病的方法。自其发展以来，已经出现了不同的型号。本研究旨在分析不同型号的 SBCE 哪种具有最佳的诊断效果。
使用 MESH 术语对广泛的医学文献进行了回顾，检索比较不同 SBCE 类型的研究。我们分析了所有比较的诊断效果，当有 2 项或更多研究比较同一型号的 SBCE 时，进行了荟萃分析。
共纳入 10 项符合条件的研究，包括 1065 例 SBCE 检查。主要适应证为 9/10 项研究中的隐匿性胃肠道出血。其中 2 项研究包括贫血、慢性腹泻和/或慢性腹痛。1 项研究的适应证为乳糜泻。9 项研究比较了不同类型的 SBCE（MiroCam、Endocapsule、OMOM 和 CapsoCam）与 PillCam（SB、SB2 和 SB3），3 项研究比较了 MiroCam 与 PillCam 和 CapsoCam 与 PillCam，2 项研究比较了 Endocapsule 与 PillCam。没有一种 SBCE 显示出优于 PillCam 的优势[OR 0.78（95%CI；0.60-1.01)]。一项研究比较了除 Pillcam 以外的 SBCE（MiroCam 与 Endocapsule）。9 项研究未发现 SBCE 之间存在统计学差异，一项研究显示 Mirocam 与 PillCam SB3 相比具有更好的诊断效果（p=0.02）。荟萃分析未再现这些 SBCE 之间的差异[OR 0.77（95%CI；0.49-1.21)]。
尽管出现了新的 SBCE 型号，但在诊断效果方面没有差异；因此，SBCE 内镜医师的表现应基于经验和可用性。
