Department of Neurology, Lehigh Valley Health Network, 1250 S Cedar Crest Blvd, Suite 405, Allentown, PA, USA.
Network Office of Research and Innovation (NORI), Lehigh Valley Health Network, Allentown, PA, USA.
Neurocrit Care. 2021 Aug;35(1):72-78. doi: 10.1007/s12028-020-01142-8. Epub 2020 Nov 16.
The modified Fisher scale (mFS) is a critical clinical and research tool for risk stratification of cerebral vasospasm. As such, the mFS is included as a common data element by the National Institute of Neurological Disorders and Stroke SAH Working Group. There are few studies assessing the interrater reliability of the mFS.
We distributed a survey to a convenience sample with snowball sampling of practicing neurointensivists and through the research survey portion of the Neurocritical Care Society Web site. The survey consisted of 15 scrollable CT scans of patients with SAH for mFS grading, two questions regarding the definitions of the scale criteria and demographics of the responding physician. Kendall's coefficient of concordance was used to determine the interrater reliability of mFS grading.
Forty-six participants (97.8% neurocritical care fellowship trained, 78% UCNS-certified in neurocritical care, median 5 years (IQR 3-6.3) in practice, treating median of 80 patients (IQR 50-100) with SAH annually from 32 institutions) completed the survey. By mFS criteria, 30% correctly identified that there is no clear measurement of thin versus thick blood, and 42% correctly identified that blood in any ventricle is scored as "intraventricular blood." The overall interrater reliability by Kendall's coefficient of concordance for the mFS was moderate (W = 0.586, p < 0.0005).
Agreement among raters in grading the mFS is only moderate. Online training tools could be developed to improve mFS reliability and standardize research in SAH.
改良 Fisher 量表(mFS)是用于评估蛛网膜下腔出血后脑血管痉挛风险分层的重要临床和研究工具。因此,mFS 被国家神经病学和卒中研究所 SAH 工作组作为常见数据元素纳入。目前,评估 mFS 评分者间可靠性的研究较少。
我们通过便利抽样对神经重症监护医生进行了问卷调查,并通过神经重症监护学会网站的研究调查部分进行了滚雪球抽样。该调查包括 15 例蛛网膜下腔出血患者的可滚动 CT 扫描,用于 mFS 分级,以及关于该量表标准定义和应答医生人口统计学的两个问题。Kendall 协和系数用于确定 mFS 分级的评分者间可靠性。
46 名参与者(97.8%接受过神经重症监护 fellowship培训,78%在神经重症监护方面获得 UCNS 认证,中位数从业年限为 5 年(IQR 3-6.3 年),每年从 32 家机构治疗中位数 80 例蛛网膜下腔出血患者)完成了调查。根据 mFS 标准,30%的人正确地认识到没有明确测量薄血与厚血,42%的人正确地认识到任何脑室中的血液都被评为“脑室积血”。Kendall 协和系数的总体评分者间可靠性为中度(W = 0.586,p < 0.0005)。
评分者在 mFS 分级中的一致性仅为中度。可以开发在线培训工具来提高 mFS 的可靠性,并使 SAH 研究标准化。