种族差异与骨微结构
Ethnic Differences in Bone Microarchitecture.
机构信息
MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, SO16 6YD, UK.
National Institute for Health Research Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
出版信息
Curr Osteoporos Rep. 2020 Dec;18(6):803-810. doi: 10.1007/s11914-020-00642-y. Epub 2020 Nov 17.
Abstract
PURPOSE OF THE REVIEW
The aim of this review is to briefly introduce updates in global fracture epidemiology and then to highlight recent contributions to understanding ethnic differences in bone density, geometry and microarchitecture and consider how these might contribute to differences in fracture risk. The review focuses on studies using peripheral quantitative computed tomography techniques.
RECENT FINDINGS
Recent studies have contributed to our understanding of the differences in fracture incidence both between countries, as well as between ethnic groups living within the same country. In terms of understanding the reasons for ethnic differences in fracture incidence, advanced imaging techniques continue to increase our understanding, though there remain relatively few studies. It is a priority to continue to understand the epidemiology, and changes in the patterns of, fracture, as well as the underlying phenotypic and biological reasons for the ethnic differences which are observed.
摘要
目的综述
本次综述的目的是简要介绍全球骨折流行病学的最新进展，然后重点介绍近期关于骨密度、几何形状和微结构的种族差异的研究成果，并探讨这些差异如何导致骨折风险的不同。综述重点关注使用外周定量计算机断层扫描技术的研究。
最新发现
最近的研究有助于我们了解不同国家之间以及同一国家内不同种族群体之间的骨折发生率差异。为了了解骨折发生率的种族差异的原因，先进的成像技术不断增加我们的认识，但此类研究仍然相对较少。优先要继续了解骨折的流行病学及其模式变化，以及观察到的种族差异的潜在表型和生物学原因。
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2
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Bone. 2020 Apr;133:115253. doi: 10.1016/j.bone.2020.115253. Epub 2020 Jan 25.
3
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J Bone Miner Res. 2020 Jan;35(1):71-80. doi: 10.1002/jbmr.3870. Epub 2019 Oct 14.
4
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