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新加坡髋部骨折:新千年的种族差异和时间趋势。

Hip fractures in Singapore: ethnic differences and temporal trends in the new millennium.

机构信息

Department of Obstetrics and Gynecology, National University of Singapore, Singapore, Singapore.

Division of Policy, Research and Evaluation, Ministry of Health, Singapore, Singapore.

出版信息

Osteoporos Int. 2019 Apr;30(4):879-886. doi: 10.1007/s00198-019-04839-5. Epub 2019 Jan 23.

Abstract

UNLABELLED

Despite an increase in absolute numbers, the age-standardized incidence of hip fractures in Singapore declined in the period 2000 to 2017. Among the three major ethnic groups, Chinese women had the highest fracture rates but were the only group to show a temporal decline.

INTRODUCTION

A study published in 2001 predicted a 30-50% increase in Singapore hip fracture incidence rates over the ensuing 30 years. To test that prediction, we examined the incidence of hip fracture in Singapore from 2000 to 2017.

METHODS

We carried out a population-based study of hip fractures among Singapore residents aged ≥ 50 years. National medical insurance claims data were used to identify admissions with a primary discharge diagnosis of hip fracture. Age-adjusted rates, based on the age distribution of the Singapore population of 2000, were analyzed separately by sex and ethnicity (Chinese, Malay, or Indian).

RESULTS

Over the 18-year study period, 36,082 first hip fractures were recorded. Total hip fracture admissions increased from 1487 to 2729 fractures/year in the years 2000 to 2017. Despite this absolute increase, age-adjusted fracture rates declined, with an average annual change of - 4.3 (95% CI - 5.0, - 3.5) and - 1.1 (95% CI - 1.7, - 0.5) fractures/100,000/year for women and men respectively. Chinese women had 1.4- and 1.9-fold higher age-adjusted rates than Malay and Indian women: 264 (95% CI 260, 267) versus 185 (95% CI 176, 193) and 141 (95% CI 132, 150) fractures/100,000/year, respectively. Despite their higher fracture rates, Chinese women were the only ethnic group exhibiting a decline, most evident in those ≥ 85 years, in age-adjusted fracture rate of - 5.3 (95% CI - 6.0, - 4.5) fractures/100,000/year.

CONCLUSION

Although the absolute number of fractures increased, steep drops in elderly Chinese women drove a reduction in overall age-adjusted hip fracture rates. Increases in the older population will lead to a rise in total number of hip fractures, requiring budgetary planning and new preventive strategies.

摘要

目的

尽管绝对数量有所增加,但 2000 年至 2017 年间,新加坡髋关节骨折的年龄标准化发病率有所下降。在三个主要种族群体中,中国女性的骨折率最高,但却是唯一显示出时间下降的群体。

方法

我们进行了一项基于人群的研究,调查了新加坡≥50 岁居民的髋关节骨折发病率。国家医疗保险索赔数据用于确定主要出院诊断为髋关节骨折的入院人数。按性别和族裔(华人、马来人或印度人)分别分析基于 2000 年新加坡人口年龄分布的年龄调整率。

结果

在 18 年的研究期间,共记录了 36082 例首次髋关节骨折。2000 年至 2017 年,全髋关节骨折入院人数从 1487 例增加到 2729 例/年。尽管绝对数量增加,但年龄调整后的骨折率下降,女性和男性的平均年变化分别为-4.3(95%CI-5.0,-3.5)和-1.1(95%CI-1.7,-0.5)例/100000/年。中国女性的年龄调整率比马来裔和印度裔女性高 1.4-1.9 倍:264(95%CI260,267)比 185(95%CI176,193)和 141(95%CI132,150)例/100000/年。尽管中国女性的骨折率较高,但她们是唯一显示出下降趋势的种族群体,在≥85 岁人群中,年龄调整后的骨折率下降最为明显,为-5.3(95%CI-6.0,-4.5)例/100000/年。

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