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音乐疗法对新生儿重症监护病房早产儿的影响:随机对照试验的系统评价和荟萃分析。

Effect of music therapy on preterm infants in neonatal intensive care unit: Systematic review and meta-analysis of randomized controlled trials.

机构信息

School of Nursing, Guangzhou University of Chinese Medicine, Guangzhou, China.

Guangzhou University City, Guangzhou, China.

出版信息

J Adv Nurs. 2021 Feb;77(2):635-652. doi: 10.1111/jan.14630. Epub 2020 Nov 17.

DOI:10.1111/jan.14630
PMID:33200833
Abstract

AIM

To systematically examine the effectiveness of music therapy on preterm infants in neonatal intensive care unit.

BACKGROUND

In recent years, the application of music therapy for preterm infants in neonatal intensive care unit has attracted more and more attention because of its clinical effects. However, there still exist disputes among different studies.

DESIGN

A systematic review and meta-analysis.

DATA SOURCES

Eleven databases were searched over the period from 1910 -4 November 2019.

REVIEW METHODS

Papers were selected for analysis in accordance with the PRISMA guidelines. The meta-analysis was carried out by using Review Manager 5.3 software.

RESULTS

A total of 13 trials involving 1,093 participants were included. Meta-analysis showed music therapy had a significant influence on preterm infant's heart rate, respiratory rate, oral feeding volume, stress level, and maternal anxiety with moderate-to-high heterogeneity among studies. Also, music therapy had no influences on oxygen saturation and behavioural state.

CONCLUSIONS

Music therapy can not only effectively improve preterm infant's heart rate, stable respiratory rate, and attenuate stress level but also exert positive impact on oral feeding volume. In addition, music therapy also plays a role in reducing maternal anxiety. However, due to the heterogeneity across studies in some outcomes, further studies with larger sample size and more stringent design should be conducted before recommendation.

IMPACT

Music therapy can significantly improve preterm infant's heart rate, respiratory rate, and stress level, as well as increase oral feeding volume. These results may exert a positive impact on well-being and quality of life in preterm infants in the neonatal intensive care unit. Hospitals can apply music therapy which has been considered a non-pharmacological and no-invasive treatment to preterm infants in the neonatal intensive care unit.

摘要

目的

系统评价音乐疗法对新生儿重症监护病房早产儿的疗效。

背景

近年来,音乐疗法在新生儿重症监护病房中的应用因其临床效果而受到越来越多的关注,但不同研究之间仍存在争议。

设计

系统评价和荟萃分析。

资料来源

检索了 1910 年 1 月至 2019 年 11 月 4 日期间的 11 个数据库。

综述方法

按照 PRISMA 指南筛选文献并进行分析。使用 Review Manager 5.3 软件进行荟萃分析。

结果

共纳入 13 项试验,涉及 1093 例患者。荟萃分析显示,音乐疗法对早产儿的心率、呼吸频率、经口喂养量、应激水平和产妇焦虑均有显著影响,但研究之间存在中度至高度异质性。音乐疗法对氧饱和度和行为状态无影响。

结论

音乐疗法不仅能有效改善早产儿的心率、稳定呼吸频率、减轻应激水平,而且对经口喂养量有积极影响。此外,音乐疗法还能降低产妇焦虑。但由于部分结局研究间存在异质性,需要进一步开展更大样本量、更严格设计的研究后,再给出推荐意见。

意义

音乐疗法能显著改善早产儿的心率、呼吸频率和应激水平,增加经口喂养量。这些结果可能对新生儿重症监护病房中早产儿的健康和生活质量产生积极影响。医院可以将音乐疗法应用于新生儿重症监护病房中的早产儿,音乐疗法被认为是非药物、非侵入性的治疗方法。

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