Sakakibara K, Kataoka M, Sakagami M, Hayashi S, Yamamoto J, Fujii Y, Takagi I, Kuwabara Y, Taniwaki S, Tsuji H
2nd Dept. of Surgery, Nagoya City Univ. Med. School.
Gan No Rinsho. 1987 Oct;33(13):1745-50.
A 32-year-old man was admitted to our hospital, complaining of an abdominal mass. An operation disclosed a large tumor, the size of a child's head, in the mesenterium of the transverse colon, with a multiple liver metastasis. A tumor resection was performed and, histologically, the tumor was diagnosed as being a choriocarcinoma. Gynecomastia was not observed. The patient died 2 months after this operation in spite of chemotherapy. An autopsy disclosed metastatic choriocarcinomas in the lungs, the liver, the peritoneum, the stomach, the adrenal glands and in the lymph nodes. The testis was found to be normal by a serial histological examination. Primary advanced adenocarcinoma, which is histologically similar to a choriocarcinoma, was found in the stomach. This case was finally diagnosed as being a gastric adenocarcinoma which showed choriocarcinomatous differentiation at various metastatic sites.
一名32岁男性因腹部肿块入院。手术发现横结肠系膜有一个如儿童头部大小的巨大肿瘤,并伴有多处肝转移。进行了肿瘤切除术,组织学检查诊断该肿瘤为绒毛膜癌。未观察到男性乳房发育。尽管进行了化疗,患者在手术后2个月死亡。尸检发现肺、肝、腹膜、胃、肾上腺和淋巴结有转移性绒毛膜癌。通过系列组织学检查发现睾丸正常。在胃中发现了组织学上与绒毛膜癌相似的原发性晚期腺癌。该病例最终诊断为胃腺癌,在多个转移部位呈现绒毛膜癌样分化。