• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

近红外光谱法作为一种过程分析技术工具，用于多参数和化学计量学监测蒸煮过程。 （你原文中“with Multiparameters and Chemometrics”前似乎少了个具体对象，我按完整语义翻译了，如果有遗漏请补充后再让我翻译）

Near-Infrared Spectroscopy as a Process Analytical Technology Tool for Monitoring the Steaming Process of with Multiparameters and Chemometrics.

作者信息

Zuo Yamin, Yang Jing, Li Chen, Deng Xuehua, Zhang Shengsheng, Wu Qing

机构信息

School of Basic Medical Sciences, Hubei Key Laboratory of Wudang Local Chinese Medicine Research, Hubei University of Medicine, 30 Renmin South Rd, Shiyan, Hubei 442000, China.

School of Basic Medical Sciences, Wuhan University, 299 Bayi Rd, Wuhan, Hubei 430072, China.

出版信息

J Anal Methods Chem. 2020 Nov 4;2020:8847277. doi: 10.1155/2020/8847277. eCollection 2020.

DOI:10.1155/2020/8847277
PMID:33204575
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7657684/
Abstract

Steaming is a vital unit operation in traditional Chinese medicine (TCM), which greatly affects the active ingredients and the pharmacological efficacy of the products. Near-infrared (NIR) spectroscopy has already been widely used as a strong process analytical technology (PAT) tool. In this study, the potential usage of NIR spectroscopy to monitor the steaming process of was explored. About 10 lab scale batches were employed to construct quantitative models to determine four chemical ingredients and moisture change during the steaming process. Gastrodin, -hydroxybenzyl alcohol, parishin B, and parishin A were modeled by different multivariate calibration models (SMLR and PLS), while the content of the moisture was modeled by principal component regression (PCR). In the optimized models, the root mean square errors of prediction (RMSEP) for gastrodin, -hydroxybenzyl alcohol, parishin B, parishin A, and moisture were 0.0181, 0.0143, 0.0132, 0.0244, and 2.15, respectively, and correlation coefficients ( ) were 0.9591, 0.9307, 0.9309, 0.9277, and 0.9201, respectively. Three other batches' results revealed that the accuracy of the model was acceptable and that was specific for next drying step. In addition, the results demonstrated the method was reliable in process performance and robustness. This method holds a great promise to replace current subjective color judgment and time-consuming HPLC or UV/Vis methods and is suitable for rapid online monitoring and quality control in the TCM industrial steaming process.

摘要

蒸制是中药中的一项关键单元操作，它对产品的活性成分和药理功效有很大影响。近红外（NIR）光谱已作为一种强大的过程分析技术（PAT）工具被广泛应用。在本研究中，探索了近红外光谱在监测天麻蒸制过程中的潜在用途。采用约10个实验室规模的批次构建定量模型，以确定蒸制过程中四种化学成分和水分的变化。天麻素、对羟基苯甲醇、巴利森苷B和巴利森苷A通过不同的多元校准模型（SMLR和PLS）进行建模，而水分含量则通过主成分回归（PCR）进行建模。在优化模型中，天麻素、对羟基苯甲醇、巴利森苷B、巴利森苷A和水分的预测均方根误差（RMSEP）分别为0.0181、0.0143、0.0132、0.0244和2.15，相关系数（r）分别为0.9591、0.9307、0.9309、0.9277和0.9201。另外三个批次的结果表明，该模型的准确性是可接受的，并且对下一步干燥步骤具有特异性。此外，结果表明该方法在过程性能和稳健性方面是可靠的。该方法有望取代当前主观的颜色判断以及耗时的高效液相色谱法或紫外/可见分光光度法，适用于中药工业蒸制过程中的快速在线监测和质量控制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/b300f8338974/JAMC2020-8847277.009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/4fadef060dc6/JAMC2020-8847277.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/1140b6d098fa/JAMC2020-8847277.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/cbb045da5515/JAMC2020-8847277.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/27eab353617b/JAMC2020-8847277.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/0fd491819afc/JAMC2020-8847277.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/d50c05d26524/JAMC2020-8847277.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/ef7a9b6512ac/JAMC2020-8847277.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/ef165395466c/JAMC2020-8847277.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/b300f8338974/JAMC2020-8847277.009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/4fadef060dc6/JAMC2020-8847277.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/1140b6d098fa/JAMC2020-8847277.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/cbb045da5515/JAMC2020-8847277.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/27eab353617b/JAMC2020-8847277.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/0fd491819afc/JAMC2020-8847277.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/d50c05d26524/JAMC2020-8847277.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/ef7a9b6512ac/JAMC2020-8847277.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/ef165395466c/JAMC2020-8847277.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5998/7657684/b300f8338974/JAMC2020-8847277.009.jpg

相似文献

1
Near-Infrared Spectroscopy as a Process Analytical Technology Tool for Monitoring the Steaming Process of with Multiparameters and Chemometrics.近红外光谱法作为一种过程分析技术工具，用于多参数和化学计量学监测蒸煮过程。 （你原文中“with Multiparameters and Chemometrics”前似乎少了个具体对象，我按完整语义翻译了，如果有遗漏请补充后再让我翻译）
J Anal Methods Chem. 2020 Nov 4;2020:8847277. doi: 10.1155/2020/8847277. eCollection 2020.
2
Near-infrared Spectroscopy as a Process Analytical Technology Tool for Monitoring the Parching Process of Traditional Chinese Medicine Based on Two Kinds of Chemical Indicators.基于两种化学指标的近红外光谱法作为监测中药烘焙过程的过程分析技术工具
Pharmacogn Mag. 2017 Apr-Jun;13(50):332-337. doi: 10.4103/pm.pm_416_16. Epub 2017 Apr 18.
3
[Quality evaluation of Gastrodiae Rhizoma standard decoction based on UPLC fingerprint and quantitative analysis multi-components method].基于超高效液相色谱指纹图谱和多成分定量分析方法的天麻标准汤剂质量评价
Zhongguo Zhong Yao Za Zhi. 2020 Oct;45(20):4909-4917. doi: 10.19540/j.cnki.cjcmm.20200622.303.
4
[Correlation between appearance characteristics and intrinsic quality of Gastrodiae Rhizoma].天麻外观特征与内在品质的相关性
Zhongguo Zhong Yao Za Zhi. 2019 Oct;44(20):4460-4466. doi: 10.19540/j.cnki.cjcmm.20190630.310.
5
Multi-parameters monitoring during traditional Chinese medicine concentration process with near infrared spectroscopy and chemometrics.近红外光谱与化学计量学用于中药浓缩过程的多参数监测。
Spectrochim Acta A Mol Biomol Spectrosc. 2018 Mar 5;192:75-81. doi: 10.1016/j.saa.2017.10.068. Epub 2017 Oct 28.
6
E-eye and FT-NIR combined with multivariate algorithms to rapidly evaluate the dynamic changes in the quality of Gastrodia elata during steaming process.E-eye 和傅里叶近红外光谱联用结合多元算法快速评价天麻蒸制过程中质量的动态变化。
Food Chem. 2024 May 1;439:138148. doi: 10.1016/j.foodchem.2023.138148. Epub 2023 Dec 6.
7
Experimental analysis on the main contents of Rhizoma gastrodiae extract and inter-transformation throughout the fermentation process of Grifola frondosa.实验分析天麻提取物的主要成分及在灰树花发酵过程中的相互转化。
Arch Pharm Res. 2013 Mar;36(3):314-21. doi: 10.1007/s12272-013-0029-2. Epub 2013 Feb 23.
8
Development and validation of in-line near-infrared spectroscopy based analytical method for commercial production of a botanical drug product.基于在线近红外光谱分析方法的开发与验证，用于商业化生产一种植物药产品。
J Pharm Biomed Anal. 2019 Sep 10;174:674-682. doi: 10.1016/j.jpba.2019.06.046. Epub 2019 Jul 2.
9
[Effects of different processing methods on effective components and sulfur dioxide residue in Gastrodiae Rhizoma].[不同炮制方法对天麻有效成分及二氧化硫残留量的影响]
Zhongguo Zhong Yao Za Zhi. 2014 Aug;39(15):2814-8.
10
pH as a Key Factor for the Quality Assurance of the Preparation of Formula Granules.pH 值是保证配方颗粒制备质量的关键因素。
Molecules. 2022 Nov 21;27(22):8091. doi: 10.3390/molecules27228091.

引用本文的文献

1
Application of digital-intelligence technology in the processing of Chinese materia medica.数字智能技术在中药加工中的应用
Front Pharmacol. 2023 Aug 24;14:1208055. doi: 10.3389/fphar.2023.1208055. eCollection 2023.
2
Development and Validation of Near-Infrared Methods for the Quantitation of Caffeine, Epigallocatechin-3-gallate, and Moisture in Green Tea Production.绿茶生产中咖啡因、表没食子儿茶素-3-没食子酸酯和水分定量近红外方法的开发与验证
J Anal Methods Chem. 2021 Nov 15;2021:9563162. doi: 10.1155/2021/9563162. eCollection 2021.

本文引用的文献

1
Discrimination of from Different Geographical Origin for Quality Evaluation Using Newly-Build Near Infrared Spectrum Coupled with Multivariate Analysis.采用近红外光谱结合多元分析技术鉴别不同产地的质量评价
Molecules. 2018 May 4;23(5):1088. doi: 10.3390/molecules23051088.
2
Novel Strategies Using Total Gastrodin and Gastrodigenin, or Total Gastrodigenin for Quality Control of Gastrodia elata.使用天麻素和天麻苷元或总天麻苷元的新策略用于天麻的质量控制。
Molecules. 2018 Jan 29;23(2):270. doi: 10.3390/molecules23020270.
3
The Content Analysis of Gastrodin and Gastrodigenin Obtained by Different Processing Methods.
不同炮制方法所得天麻素与天麻苷元的含量分析
J Chromatogr Sci. 2018 Jan 1;56(1):65-67. doi: 10.1093/chromsci/bmx085.
4
Classification and quantitation of milk powder by near-infrared spectroscopy and mutual information-based variable selection and partial least squares.基于近红外光谱和互信息变量选择及偏最小二乘法的奶粉分类与定量分析。
Spectrochim Acta A Mol Biomol Spectrosc. 2018 Jan 15;189:183-189. doi: 10.1016/j.saa.2017.08.034. Epub 2017 Aug 10.
5
On-line monitoring of extraction process of Flos Lonicerae Japonicae using near infrared spectroscopy combined with synergy interval PLS and genetic algorithm.采用近红外光谱技术结合协同区间偏最小二乘法和遗传算法对金银花提取过程进行在线监测。
Spectrochim Acta A Mol Biomol Spectrosc. 2017 Jul 5;182:73-80. doi: 10.1016/j.saa.2017.04.004. Epub 2017 Apr 6.
6
Vasodilatory effects and underlying mechanisms of the ethyl acetate extracts from Gastrodia elata.天麻乙酸乙酯提取物的血管舒张作用及其潜在机制。
Can J Physiol Pharmacol. 2017 May;95(5):564-571. doi: 10.1139/cjpp-2016-0407. Epub 2016 Dec 17.
7
[Study on the Rapid Evaluation of Total Volatile Basic Nitrogen (TVB-N) of Mutton by Hyperspectral Imaging Technique].[基于高光谱成像技术的羊肉挥发性盐基氮（TVB-N）快速评估研究]
Guang Pu Xue Yu Guang Pu Fen Xi. 2016 Mar;36(3):806-10.
8
The rhizome of Gastrodia elata Blume - An ethnopharmacological review.天麻的根茎——民族药理学综述。
J Ethnopharmacol. 2016 Aug 2;189:361-85. doi: 10.1016/j.jep.2016.06.057. Epub 2016 Jul 1.
9
Specific targeted quantification combined with non-targeted metabolite profiling for quality evaluation of Gastrodia elata tubers from different geographical origins and cultivars.采用特定靶向定量与非靶向代谢物谱分析相结合的方法对不同地理来源和品种的天麻块茎进行质量评价。
J Chromatogr A. 2016 Jun 10;1450:53-63. doi: 10.1016/j.chroma.2016.04.077. Epub 2016 Apr 29.
10
An approach combining real-time release testing with near-infrared spectroscopy to improve quality control efficiency of Rhizoma paridis.一种将实时释放测试与近红外光谱相结合的方法，以提高重楼的质量控制效率。
Spectrochim Acta A Mol Biomol Spectrosc. 2016 Mar 15;157:186-191. doi: 10.1016/j.saa.2016.01.001. Epub 2016 Jan 6.