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[运用无创方法评估脑脊液系统的储备空间]

[Evaluation of the reserve spaces of the cerebrospinal system by using noninvasive methods].

作者信息

Simonov L G, Tsaturian A K, Saribekian A S, Shmidt L G

出版信息

Kosm Biol Aviakosm Med. 1987 Sep-Oct;21(5):62-5.

PMID:3320503
Abstract

This paper presents a theory according to which fluid volumes and pressures in the cerebrospinal system should be related nonlinearly rather than exponentially. The curve describing elasticity E as a function of pressure P should have two almost linear segments separated by an intercept. This concept is based on experimental and model data suggesting that the cerebrospinal system can be viewed as an elastic cavity which can, at normal and low pressures, trap an additional volume of any CSF component and shift other components; as a result, this leads to a linear increase in pressure within the cavity. The theoretical concepts found support in comparative invasive-noninvasive studies of the intracranial fluid with the aid of ultrasonic examination and in postural tests to which patients with cerebral lesions were exposed. A noninvasive technique for measuring fluid volumes and pressures in the cerebrospinal cavity was developed. The technique can be used as a diagnostic tool in the case of intracranial distension.

摘要

本文提出了一种理论,根据该理论,脑脊液系统中的液体体积和压力应呈非线性关系,而非指数关系。描述弹性E作为压力P函数的曲线应具有两个由一个截距分隔的近似线性段。这一概念基于实验和模型数据,表明脑脊液系统可被视为一个弹性腔,在正常和低压情况下,它可以捕获额外体积的任何脑脊液成分并使其他成分发生移位;结果,这导致腔内压力呈线性增加。在借助超声检查对颅内液体进行的侵入性与非侵入性对比研究以及对脑部病变患者进行的体位测试中,这些理论概念得到了支持。开发了一种用于测量脑脊液腔内液体体积和压力的非侵入性技术。该技术可作为颅内扩张情况下的诊断工具。

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