颠覆性协同作用：人类遗传学与临床辅助生殖的融合。
Disruptive Synergy: Melding of Human Genetics and Clinical Assisted Reproduction.
机构信息
Warren Alpert Medical School, Brown University, Providence, RI 02906, USA.
Petrie-Flom Center for Health Law Policy, Biotechnology, and Bioethics, Harvard Law School, Harvard University, Cambridge, MA, USA.
出版信息
Cell Rep Med. 2020 Sep 22;1(6):100093. doi: 10.1016/j.xcrm.2020.100093.
Abstract
The melding of human genetics with clinical assisted reproduction, now all but self-evident, gave flight to diagnostic and therapeutic approaches previously deemed infeasible. Preimplantation genetic diagnosis, mitochondrial replacement techniques, and remedial germline editing are particularly noteworthy. Here we explore the relevant disruption brought forth by coalescence of these mutually enabling disciplines with the regulatory and legal implications thereof.
摘要
人类遗传学与临床辅助生殖的融合，如今几乎不言而喻，为以前认为不可行的诊断和治疗方法提供了发展空间。胚胎植入前遗传学诊断、线粒体替换技术和矫正种系编辑技术尤其值得关注。在这里，我们探讨了这些相互促进的学科融合所带来的相关干扰，以及由此产生的监管和法律影响。
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