Burnet Institute, Melbourne, VIC.
University of Copenhagen, Copenhagen, Denmark.
Med J Aust. 2021 Feb;214(2):79-83. doi: 10.5694/mja2.50845. Epub 2020 Nov 18.
To assess the risks associated with relaxing coronavirus disease 2019 (COVID-19)-related physical distancing restrictions and lockdown policies during a period of low viral transmission.
Network-based viral transmission risks in households, schools, workplaces, and a variety of community spaces and activities were simulated in an agent-based model, Covasim.
The model was calibrated for a baseline scenario reflecting the epidemiological and policy environment in Victoria during March-May 2020, a period of low community viral transmission.
Policy changes for easing COVID-19-related restrictions from May 2020 were simulated in the context of interventions that included testing, contact tracing (including with a smartphone app), and quarantine.
Increase in detected COVID-19 cases following relaxation of restrictions.
Policy changes that facilitate contact of individuals with large numbers of unknown people (eg, opening bars, increased public transport use) were associated with the greatest risk of COVID-19 case numbers increasing; changes leading to smaller, structured gatherings with known contacts (eg, small social gatherings, opening schools) were associated with lower risks. In our model, the rise in case numbers following some policy changes was notable only two months after their implementation.
Removing several COVID-19-related restrictions within a short period of time should be undertaken with care, as the consequences may not be apparent for more than two months. Our findings support continuation of work from home policies (to reduce public transport use) and strategies that mitigate the risk associated with re-opening of social venues.
评估在病毒传播率较低期间放宽与 2019 年冠状病毒病(COVID-19)相关的身体距离限制和封锁政策相关的风险。
基于代理的 Covasim 模型模拟了家庭、学校、工作场所以及各种社区空间和活动中的病毒网络传播风险。
该模型针对反映 2020 年 3 月至 5 月维多利亚州流行病学和政策环境的基线情况进行了校准,这是社区病毒传播率较低的时期。
模拟了从 2020 年 5 月开始放宽与 COVID-19 相关限制的政策变化,这些变化是在包括测试、接触者追踪(包括使用智能手机应用程序)和隔离在内的干预措施的背景下进行的。
放松限制后检测到的 COVID-19 病例增加。
促进个人与大量未知人员接触的政策变化(例如,开放酒吧、增加公共交通使用)与 COVID-19 病例数量增加的风险最大;导致与已知联系人进行较小、结构化聚会的变化(例如,小型社交聚会、开放学校)与较低的风险相关。在我们的模型中,一些政策变化后的病例数增加仅在实施两个月后才变得明显。
在短时间内取消几项与 COVID-19 相关的限制应谨慎进行,因为其后果可能需要两个多月的时间才能显现。我们的研究结果支持继续实施在家工作政策(以减少公共交通使用)和减轻与社交场所重新开放相关风险的策略。