Legrain M, Rottembourg J, Jacobs C
Diabete Metab. 1985 Feb;11(1):51-69.
The number of diabetics with end stage renal disease (ESRD) is growing. The best treatment at the lowest cost possible should be offered to all diabetics if therapeutic facilities are available. Such a policy requires that all dialysis methods and transplantation should be available and that transfer from one method to another should always be allowable. Results observed among insulin and non insulin-dependent diabetics are improving steadily, even in the older age group. However they are inferior to those observed in non diabetic people of the same age. Adequate medical care, including excellent control of high blood pressure and good control of blood glucose levels should reduce the frequency of severe complications including cardiac, ocular and peripheral vascular lesions. In diabetic patients under forty years of age, renal transplantation using a kidney from a cadaver or a related donor should be the first choice. However, for most patients dialysis methods are required as the only treatment or while waiting for a transplant. Very encouraging results are obtained with both hemodialysis and peritoneal dialysis. If home dialysis is considered, continuous ambulatory peritoneal dialysis (CAPD) offers the opportunity to treat many insulin-dependent or non dependent diabetics at home even those in the high risk population because of age and/or cardio-vascular instability. CAPD offers excellent control of blood glucose levels using the intraperitoneal route to administer insulin. Results obtained are discussed from data in the literature and from a survey of 124 insulin-dependent diabetic cases with ESRD treated in the Department of Nephrology of the Hospital de La Pitié from 1973 to 1984.
患有终末期肾病(ESRD)的糖尿病患者数量正在增加。如果有治疗设施,应向所有糖尿病患者提供成本最低的最佳治疗方法。这样一项政策要求所有透析方法和移植都应可行,并且从一种方法转换到另一种方法应始终是允许的。在胰岛素依赖型和非胰岛素依赖型糖尿病患者中观察到的结果正在稳步改善,即使在老年人群中也是如此。然而,这些结果不如在同年龄的非糖尿病患者中观察到的结果。充分的医疗护理,包括对高血压的良好控制和对血糖水平的良好控制,应减少包括心脏、眼部和外周血管病变在内的严重并发症的发生频率。对于40岁以下的糖尿病患者,使用尸体或亲属供体的肾脏进行肾移植应是首选。然而,对于大多数患者来说,透析方法是唯一的治疗方法或在等待移植期间所需的治疗方法。血液透析和腹膜透析都取得了非常令人鼓舞的结果。如果考虑家庭透析,持续非卧床腹膜透析(CAPD)为在家中治疗许多胰岛素依赖型或非胰岛素依赖型糖尿病患者提供了机会,甚至包括那些因年龄和/或心血管不稳定而处于高风险人群中的患者。CAPD通过腹膜内途径注射胰岛素,能很好地控制血糖水平。我们根据文献数据以及对1973年至1984年在拉皮蒂医院肾病科接受治疗的124例胰岛素依赖型糖尿病ESRD患者的调查结果,对所获得的结果进行了讨论。