Tahlan Karishma, Tanveer Nadeem, Kumar Harresh, Diwan Himanshi
Department of Pathology, University College of Medical Sciences, Delhi, India.
J Cutan Aesthet Surg. 2020 Jul-Sep;13(3):233-236. doi: 10.4103/JCAS.JCAS_148_19.
Glial heterotopias are the displacement of neuroglial tissue in extracranial sites. Nasal glial heterotopias can be of three types-extranasal, intranasal and mixed. Root of the nose is the most common location. These are rare anomalies with an incidence of 1 case in 20,000-40,000 live births. Here we report the case of a 6-month-old infant with a congenital mass located at the root of the nose. Non-contrast computed tomography studies showed no evidence of intracranial communication of the lesion. The mass was excised, and on histopathological examination, it showed glial tissue with astrocytes in a fibrillary background and fibroconnective tissue. Masson's trichrome stain showed the red staining of the glial tissue, whereas the background fibrosis was stained blue. On immunohistochemistry, glial fibrillary acidic protein was positive. Hence, the diagnosis of nasal glial heterotropia was made. The patient had an uneventful postoperative period.
胶质异位是神经胶质组织在颅外部位的移位。鼻胶质异位可分为三种类型——鼻外、鼻内和混合型。鼻根部是最常见的部位。这些是罕见的异常情况，在20000 - 40000例活产中发生率为1例。在此我们报告一例6个月大的婴儿，其鼻根部有一个先天性肿块。非增强计算机断层扫描研究显示该病变无颅内连通的证据。肿块被切除，组织病理学检查显示在纤维背景中有含星形胶质细胞的胶质组织和纤维结缔组织。Masson三色染色显示胶质组织呈红色染色，而背景纤维化呈蓝色染色。免疫组织化学检查显示胶质纤维酸性蛋白呈阳性。因此，诊断为鼻胶质异位。该患者术后恢复顺利。
