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鼻先天性畸形:从胚胎学到外科治疗

Congenital Anomalies of the Nose: From Embryologic to Surgical Treatment.

作者信息

Deftereou Theodora-Eleftheria, Karapepera Vaia, Lialiaris Stergios, Fotiadis George, Chaidas Konstantinos, Katotomichelakis Michail

机构信息

Laboratory of Histology-Embryology, Democritus University of Thrace, Alexandroupolis, GRC.

Ear, Nose, and Throat (ENT) Clinic, General Hospital of Ioannina "G. Chatzikosta", Ioannnina, GRC.

出版信息

Cureus. 2025 Aug 5;17(8):e89397. doi: 10.7759/cureus.89397. eCollection 2025 Aug.

DOI:10.7759/cureus.89397
PMID:40918896
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12409691/
Abstract

The nose, a facial organ, not only plays a crucial role in olfaction and respiration but also has a major impact on the overall anatomy of the face. However, congenital anomalies affecting the nose can be challenging as they require both functional impairments and cosmetic concerns. Facial maldevelopments during the early embryonic period induce a wide-ranging nasal deformity. Understanding the etiology of these anomalies is essential for healthcare professionals involved in diagnosis, treatment, and management. Based on current literature, this review aims to present the spectrum of congenital disorders of the nose and a summary of their embryologic etiology, clinical presentations, and therapeutic interventions.

摘要

鼻子作为面部器官,不仅在嗅觉和呼吸中起着关键作用,而且对面部的整体解剖结构也有重大影响。然而,影响鼻子的先天性异常可能具有挑战性,因为它们既涉及功能障碍,又关乎外观问题。胚胎早期的面部发育异常会导致各种各样的鼻畸形。了解这些异常的病因对于参与诊断、治疗和管理的医疗专业人员至关重要。基于当前文献,本综述旨在介绍鼻子先天性疾病的范围,并总结其胚胎学病因、临床表现和治疗干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b97f/12409691/8318a9e66a4b/cureus-0017-00000089397-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b97f/12409691/2fab54af4b55/cureus-0017-00000089397-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b97f/12409691/d6f19f58a584/cureus-0017-00000089397-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b97f/12409691/1859fe1c89da/cureus-0017-00000089397-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b97f/12409691/8318a9e66a4b/cureus-0017-00000089397-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b97f/12409691/2fab54af4b55/cureus-0017-00000089397-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b97f/12409691/d6f19f58a584/cureus-0017-00000089397-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b97f/12409691/1859fe1c89da/cureus-0017-00000089397-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b97f/12409691/8318a9e66a4b/cureus-0017-00000089397-i04.jpg

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本文引用的文献

1
Unveiling Nasal Glial Heterotopia: A Pathological Perspective.揭开鼻胶质异位症:病理学视角
Cureus. 2024 Apr 30;16(4):e59341. doi: 10.7759/cureus.59341. eCollection 2024 Apr.
2
The Differential Diagnosis of Congenital Developmental Midline Nasal Masses: Histopathological, Clinical, and Radiological Aspects.先天性发育性中线鼻腔肿物的鉴别诊断:组织病理学、临床及影像学方面
Diagnostics (Basel). 2023 Aug 29;13(17):2796. doi: 10.3390/diagnostics13172796.
3
Nasal Construction in Congenital Arhinia Due to Novel SMCHD1 Gene Variant.
先天性无鼻畸形患者的鼻腔构建:一种新型 SMCHD1 基因突变所致。
J Craniofac Surg. 2023 May 1;34(3):849-854. doi: 10.1097/SCS.0000000000009261. Epub 2023 Mar 22.
4
Two Forehead Flaps for Nasal Reconstruction of a Patient with Arhinia.采用双额部皮瓣修复无鼻畸形患者的鼻缺损
World J Plast Surg. 2022;11(3):103-108. doi: 10.52547/wjps.11.3.103.
5
Nasal glial heterotopia: a systematic review of the literature and case report.鼻内神经胶质异位症:文献系统综述与病例报告
Acta Otorhinolaryngol Ital. 2022 Aug;42(4):317-324. doi: 10.14639/0392-100X-N1977.
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Prenatal Diagnosis of Arhinia.无鼻畸形的产前诊断。
AJP Rep. 2022 Aug 6;12(2):e127-e130. doi: 10.1055/s-0042-1748521. eCollection 2022 Apr.
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Paediatric nasal dermoid: evaluation and management.小儿鼻皮样囊肿:评估与处理
Curr Opin Otolaryngol Head Neck Surg. 2021 Dec 1;29(6):487-491. doi: 10.1097/MOO.0000000000000765.
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Analysis of National Outcomes for Simple Versus Complex Nasal Dermoid Cyst Excision.单纯性与复杂性鼻部皮样囊肿切除术的全国性结果分析。
J Craniofac Surg. 2021 May 1;32(3):e281-e283. doi: 10.1097/SCS.0000000000007160.
9
A Rare Case of Nasal Glial Heterotopia in an Infant.婴儿鼻内神经胶质异位症1例罕见病例
J Cutan Aesthet Surg. 2020 Jul-Sep;13(3):233-236. doi: 10.4103/JCAS.JCAS_148_19.
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Pai syndrome: a review.派伊综合征:综述。
Childs Nerv Syst. 2020 Nov;36(11):2635-2640. doi: 10.1007/s00381-020-04788-z. Epub 2020 Jul 10.