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马里兰州每日仅使用电子烟者的电子烟使用行为及设备特征:对产品毒性的启示

E-cigarette use behaviors and device characteristics of daily exclusive e-cigarette users in Maryland: Implications for product toxicity.

作者信息

Aherrera Angela, Aravindakshan Atul, Jarmul Stephanie, Olmedo Pablo, Chen Rui, Cohen Joanna E, Navas-Acien Ana, Rule Ana M

机构信息

Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, United States.

Division of Pediatric Pulmonary Medicine, Johns Hopkins School of Medicine, Baltimore, United States.

出版信息

Tob Induc Dis. 2020 Nov 10;18:93. doi: 10.18332/tid/128319. eCollection 2020.

Abstract

INTRODUCTION

Few studies to date have characterized daily exclusive e-cigarette users, device characteristics, and use behaviors. This study describes daily e-cigarette user characteristics, and assesses the association between user behaviors and demographics.

METHODS

From 2015-2017, 100 daily exclusive e-cigarette users and 50 non-users were recruited in Maryland, USA. Sociodemographic characteristics, health status, e-cigarette/tobacco use behaviors, device characteristics, and reasons for e-cigarette use were collected by interview. Chi-squared tests (categorical variables), Student's t-test (continuous variables), and linear regressions were used to assess relationships between variables.

RESULTS

Most daily exclusive e-cigarette users were men, White, former smokers, used MODs/tanks, and vaped on average 365 puffs/day (SD: 720). A third of users first vaped within 5 minutes of waking in the morning, and 56% vaped throughout the day. E-liquid consumption ranged from 5-240 mL/week (median: 32.5), with nicotine concentration 0-24 mg/mL (median: 3). E-cigarette users were more likely to report wheezing/whistling and hypertension than controls, although the finding was not statistically significant after adjustment. Less than half planned to quit vaping.

CONCLUSIONS

Daily e-cigarette users between 2015-2017 most commonly vaped MOD/tank devices. Being male and of lower education was associated with higher usage. Daily users with no intention to quit may be at risk for increased exposure to emissions from e-cigarettes that include inorganic (metals) and organic (e.g. acrolein, formaldehyde) compounds with known toxic effects, particularly to the lung. Further research is needed to characterize the long-term health effects of daily e-cigarette use.

摘要

引言

迄今为止,很少有研究对每日仅使用电子烟的用户、设备特征及使用行为进行描述。本研究描述了每日电子烟用户的特征,并评估了用户行为与人口统计学之间的关联。

方法

2015年至2017年期间,在美国马里兰州招募了100名每日仅使用电子烟的用户和50名非用户。通过访谈收集社会人口统计学特征、健康状况、电子烟/烟草使用行为、设备特征及使用电子烟的原因。采用卡方检验(分类变量)、学生t检验(连续变量)和线性回归来评估变量之间的关系。

结果

大多数每日仅使用电子烟的用户为男性、白人、既往吸烟者,使用模组/储液罐式电子烟,平均每天吸365口(标准差:720)。三分之一的用户在早晨醒来后5分钟内首次吸电子烟,56%的用户全天都吸。电子烟液消耗量为每周5至240毫升(中位数:32.5),尼古丁浓度为0至24毫克/毫升(中位数:3)。与对照组相比,电子烟用户更有可能报告喘息/哮鸣和高血压,不过调整后该结果无统计学意义。不到一半的人计划戒烟。

结论

2015年至2017年期间的每日电子烟用户最常使用模组/储液罐式设备。男性及受教育程度较低与更高的使用量相关。无意戒烟的每日用户可能面临接触电子烟排放物增加的风险,这些排放物包括具有已知毒性作用的无机(金属)和有机(如丙烯醛、甲醛)化合物,尤其是对肺部的毒性。需要进一步研究以确定每日使用电子烟的长期健康影响。

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