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对盐酸吡哆醇(维生素B)作为所有动物物种饲料添加剂的授权续展申请的评估。

Assessment of the application for renewal of authorisation of pyridoxine hydrochloride (vitamin B) as a feed additive for all animal species.

作者信息

Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Dusemund Birgit, Fašmon Durjava Mojca, Kouba Maryline, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Sanz Yolanda, Villa Roberto Edoardo, Woutersen Ruud, Anguita Montserrat, Galobart Jaume, Holczknecht Orsolya, Tarrés-Call Jordi, Pettenati Elisa, Pizzo Fabiola, Manini Paola

出版信息

EFSA J. 2020 Nov 13;18(11):e06289. doi: 10.2903/j.efsa.2020.6289. eCollection 2020 Nov.

Abstract

Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the assessment of the application for renewal of authorisation of pyridoxine hydrochloride (vitamin B) produced by chemical synthesis as a feed additive for all animal species. The applicant has provided data demonstrating that the additive in the market complies with the conditions of the authorisation. The FEEDAP Panel confirms that the use of pyridoxine hydrochloride under the current authorised conditions of use is safe for the target species, the consumers and the environment. Pyridoxine hydrochloride is non-irritant to skin and eyes and is not a skin sensitiser. It may cause photosensitisation. In the absence of inhalation toxicity studies, adverse effects in the respiratory tract cannot be fully excluded. There is no need for assessing the efficacy of the additive in the context of the renewal of the authorisation.

摘要

应欧盟委员会的要求,欧洲食品安全局动物饲料添加剂和产品或物质专家小组(FEEDAP)被要求就化学合成生产的盐酸吡哆醇(维生素B6)作为所有动物物种饲料添加剂的授权续展申请评估提供科学意见。申请人提供的数据表明,市场上的添加剂符合授权条件。FEEDAP小组确认,在当前授权使用条件下使用盐酸吡哆醇对目标物种、消费者和环境是安全的。盐酸吡哆醇对皮肤和眼睛无刺激性,不是皮肤致敏剂。它可能会引起光致敏。由于缺乏吸入毒性研究,不能完全排除对呼吸道的不良影响。在授权续展时无需评估该添加剂的功效。

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