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腮腺黏液表皮样癌表现为外生性溃疡性肿物:源于广泛神经包绕的手术挑战

Mucoepidermoid Carcinoma of the Parotid Gland Presenting as a Fungating Exophytic Mass: A Surgical Challenge Rooted in Extensive Nerve Encasement.

作者信息

Almas Talal, Hussain Salman, Ehtesham Maryam, Alsufyani Reema, Khan Muhammad Kashif

机构信息

Internal Medicine, Royal College of Surgeons in Ireland, Dublin, IRL.

Surgical Oncology, Federal Government Poly Clinic (Post Graduate Medical Institute), Islamabad, PAK.

出版信息

Cureus. 2020 Oct 16;12(10):e10990. doi: 10.7759/cureus.10990.

DOI:10.7759/cureus.10990
PMID:33209546
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7667710/
Abstract

Parotid glands, which are predominantly composed of serous acini, are the largest salivary glands in the human body. Mucoepidermoid carcinoma (MEC) of the parotid gland is the most common parotid tumour that routinely presents as a painless, fixed mass below the ears. However, its presentation as a fungating mass remains exceedingly rare. Due to the intimate anatomical relationship between the parotid gland and the facial nerve, parotid malignancies can culminate in facial nerve palsy, posing an onerous surgical challenge. In this paper, we chronicle the case of a male who presented with a fungating/exophytic mass and facial nerve weakness. A superficial parotidectomy was performed, and the eventual histopathological workup divulged an advanced mucoepidermoid parotid carcinoma entirely encasing the marginal mandibular nerve. Consequently, the marginal mandibular nerve was sacrificed, alluding to the remarkable surgical challenge encountered. Clinically, this manifested as an impairment of the motor function in the patient's left lower lip.

摘要

腮腺主要由浆液性腺泡组成,是人体最大的唾液腺。腮腺黏液表皮样癌(MEC)是最常见的腮腺肿瘤,通常表现为耳下无痛、固定的肿块。然而,其表现为溃疡性肿块的情况仍然极为罕见。由于腮腺与面神经之间存在密切的解剖关系,腮腺恶性肿瘤可能导致面神经麻痹,带来艰巨的手术挑战。在本文中,我们记录了一名男性患者的病例,该患者表现为溃疡性/外生性肿块和面神经无力。进行了腮腺浅叶切除术,最终的组织病理学检查显示为晚期黏液表皮样腮腺癌,完全包裹了下颌缘支神经。因此,牺牲了下颌缘支神经,这暗示了所遇到的巨大手术挑战。临床上,这表现为患者左下唇运动功能受损。

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本文引用的文献

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A Rare Case of Mucoepidermoid Carcinoma of Parotid with Mandibular Metastasis.1例罕见的腮腺黏液表皮样癌伴下颌骨转移病例
Ann Maxillofac Surg. 2019 Jan-Jun;9(1):205-207. doi: 10.4103/ams.ams_276_18.
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