Shojaei Mohammad, Jahromi Abdolreza Sotoodeh, Karamatollah Rahmanian
Research Center for Noncommunicable Diseases, Jahrom University of Medical Sciences, Jahrom, Iran.
J Family Med Prim Care. 2020 Sep 30;9(9):4705-4711. doi: 10.4103/jfmpc.jfmpc_723_20. eCollection 2020 Sep.
Nowadays, obesity is an important health problem and pulse pressure (PP) is a good predictor of cardiovascular events. The aim of study was to determine the association of obesity and PP with hypertension (HTN) in individuals aged 30 years or older in the urban population of Jahrom, Iran.
In this study, we used a multistage stratified sampling method to select participants among the urban population aged 30 years or older. Height, weight, and blood pressure were obtained by a trained physician. Obesity was defined according to the World Health Organization classification. Angina was assessed with reliable and validate Rose questionnaire. Data were record by SPSS-16. Categorical and continues variables analyzed by Chi-squared, independent -test, and one-way ANOVA test. Binary logistic regression analysis method was used for the association of PP and obesity with HTN and Rose angina that adjusted for age, gender, education class, marital status, smoking, total cholesterol, triglyceride, low-density lipoprotein, and high-density lipoprotein. A < 0.05 was considered as statistical significance.
The prevalence of obesity was 18.1% that was greater in women (24.8% vs. 9.9%, < 0.001). The prevalence of Rose angina and HTN in obese individuals were more than in normal weight individuals (24.8% vs. 16.4%, = 0.027) and (42.0% vs. 31.1%, < 0.001), respectively. Furthermore, patients in higher PP groups were older, were more possible to had HTN and had greater diastolic blood pressure (DBP), systolic blood pressure (SBP), and mean arterial pressure (MAP) in compared to individuals in the lower PP group. The individuals with HTN had greater DBP, SBP, MAP, PP, and body mass index (BMI) than individuals without HTN. However, individuals who had Rose angina, only had higher PP and BMI in compared to ones without Rose angina. The obese individuals had 1.97 (1.22-3.17, = 0.005) fold for HTN risk than individuals with normal weight. In addition, PP weakly increased the risk of HTN about 1.09 fold (1.07-1.10, < 0.001). However, Rose angina was associated only to overweight status (odds ratio = 1.51, confidence interval 95%: 1.03-2.20), = 0.035) than individuals in normal weight group.
Obesity and PP were higher in hypertensive individuals and overweight in individuals with Rose angina. It is time to pay more attention to abnormal BMI.
如今，肥胖是一个重要的健康问题，脉压（PP）是心血管事件的良好预测指标。本研究的目的是确定伊朗贾赫罗姆城市人口中30岁及以上个体的肥胖和脉压与高血压（HTN）之间的关联。
在本研究中，我们采用多阶段分层抽样方法从30岁及以上的城市人口中选取参与者。身高、体重和血压由经过培训的医生测量。肥胖根据世界卫生组织的分类进行定义。使用可靠且经过验证的罗斯问卷评估心绞痛情况。数据由SPSS - 16记录。分类变量和连续变量分别采用卡方检验、独立样本t检验和单因素方差分析进行分析。采用二元逻辑回归分析方法分析脉压和肥胖与高血压及罗斯心绞痛之间的关联，并对年龄、性别、教育程度、婚姻状况、吸烟、总胆固醇、甘油三酯、低密度脂蛋白和高密度脂蛋白进行校正。P < 0.05被认为具有统计学意义。
肥胖患病率为18.1%，女性患病率更高（24.8%对9.9%，P < 0.001）。肥胖个体中罗斯心绞痛和高血压的患病率分别高于正常体重个体（24.8%对16.4%，P = 0.027）和（42.0%对31.1%，P < 0.001）。此外，与低脉压组个体相比，高脉压组患者年龄更大，更有可能患有高血压，舒张压（DBP）、收缩压（SBP）和平均动脉压（MAP）更高。高血压患者的DBP、SBP、MAP、PP和体重指数（BMI）高于非高血压患者。然而，与无罗斯心绞痛的个体相比，有罗斯心绞痛的个体仅PP和BMI较高。肥胖个体患高血压的风险是正常体重个体的1.97倍（1.22 - 3.17，P = 0.005）。此外，脉压使高血压风险微弱增加约1.09倍（1.07 - 1.10，P < 0.001）。然而，与正常体重组个体相比，罗斯心绞痛仅与超重状态相关（比值比 = 1.51，95%置信区间：1.03 - 2.20，P = 0.035）。
高血压个体的肥胖和脉压较高；罗斯心绞痛个体超重。是时候更加关注异常的BMI了。
