Winston D J, Balsley G E, Rhodes J, Linné S R
Arch Intern Med. 1977 Sep;137(9):1192-5.
Trichosporon is a frequent cause of superficial mycotic infections but has rarely been associated with invasive disease. A patient undergoing bone marrow transplantation who died from disseminated Trichosporon capitatum infection with endocarditis is reported, and the clinical spectrum of human infection caused by fungi of this genus is reviewed. To our knowledge, this is the first reported case of clearly invasive disease caused by this specific organism and emphasizes the expanding spectrum of unusual infections in the severely immunosuppressed patient.
毛孢子菌是浅表真菌感染的常见病因，但很少与侵袭性疾病相关。本文报告了1例接受骨髓移植的患者，该患者死于播散性头状毛孢子菌感染合并心内膜炎，并对该属真菌引起的人类感染的临床谱进行了综述。据我们所知，这是首例由这种特定病原体引起的明确侵袭性疾病的报告病例，强调了严重免疫抑制患者中不寻常感染谱的不断扩大。
