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Can Urol Assoc J. 2021 Jun;15(6):202-206. doi: 10.5489/cuaj.6947.
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Efficacy and safety of platelet-rich plasma intracavernous injection for patients with erectile dysfunction: A systematic review, meta-analysis, and meta-regression.阴茎海绵体内注射富血小板血浆治疗勃起功能障碍患者的疗效与安全性:一项系统评价、荟萃分析和荟萃回归分析
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本文引用的文献

1
The good, bad, and the ugly of regenerative therapies for erectile dysfunction.勃起功能障碍再生疗法的利弊
Transl Androl Urol. 2020 Mar;9(Suppl 2):S252-S261. doi: 10.21037/tau.2019.10.06.
2
A Review of Current and Emerging Therapeutic Options for Erectile Dysfunction.勃起功能障碍的现有及新兴治疗选择综述
Med Sci (Basel). 2019 Aug 29;7(9):91. doi: 10.3390/medsci7090091.
3
Platelet-Rich Plasma for the Treatment of Low Back Pain: a Comprehensive Review.富血小板血浆治疗腰痛:全面综述。
Curr Pain Headache Rep. 2019 Jul 3;23(7):52. doi: 10.1007/s11916-019-0797-6.
4
The global prevalence of erectile dysfunction: a review.勃起功能障碍的全球患病率:一项综述。
BJU Int. 2019 Oct;124(4):587-599. doi: 10.1111/bju.14813. Epub 2019 Jul 2.
5
Platelet-Rich Plasma Therapy for Male Sexual Dysfunction: Myth or Reality?富血小板血浆疗法治疗男性性功能障碍:是神话还是现实?
Sex Med Rev. 2020 Jan;8(1):106-113. doi: 10.1016/j.sxmr.2019.02.002. Epub 2019 Mar 19.
6
Platelet-Rich Plasma and Treatment of Erectile Dysfunction: Critical Review of Literature and Global Trends in Platelet-Rich Plasma Clinics.富血小板血浆与勃起功能障碍治疗:文献综述与富血小板血浆临床全球趋势的批判性分析。
Sex Med Rev. 2019 Apr;7(2):306-312. doi: 10.1016/j.sxmr.2018.12.006. Epub 2019 Mar 2.
7
Recent advances in the understanding and management of erectile dysfunction.勃起功能障碍的认识与治疗的最新进展
F1000Res. 2019 Jan 25;8. doi: 10.12688/f1000research.16576.1. eCollection 2019.
8
Long-term therapeutic effect of cell therapy on improvement in erectile function in a rat model with pelvic neurovascular injury.细胞治疗对骨盆神经血管损伤大鼠模型勃起功能改善的长期治疗效果。
BJU Int. 2019 Jul;124(1):145-154. doi: 10.1111/bju.14631. Epub 2019 Feb 27.
9
Platelet-rich plasma therapy and reproductive medicine.富血小板血浆治疗与生殖医学。
J Assist Reprod Genet. 2018 May;35(5):753-756. doi: 10.1007/s10815-018-1159-8. Epub 2018 Mar 21.
10
Safety and feasibility of platelet rich fibrin matrix injections for treatment of common urologic conditions.富血小板纤维蛋白基质注射治疗常见泌尿科疾病的安全性和可行性。
Investig Clin Urol. 2018 Jan;59(1):61-65. doi: 10.4111/icu.2018.59.1.61. Epub 2017 Dec 21.

富血小板血浆用于治疗勃起功能障碍的可得性、相关成本及疗效:对当前出版物及加拿大数据的综述

Availability of platelet-rich plasma for treatment of erectile dysfunction and associated costs and efficacy: A review of current publications and Canadian data.

作者信息

Britt Deron, Blankstein Udi, Lenardis Matthew, Millman Alexandra, Grober Ethan, Krakowsky Yonah

机构信息

University of Ottawa, Faculty of Medicine, Ottawa, ON, Canada.

Division of Urology, University of Toronto, Toronto, ON, Canada.

出版信息

Can Urol Assoc J. 2021 Jun;15(6):202-206. doi: 10.5489/cuaj.6947.

DOI:10.5489/cuaj.6947
PMID:33212009
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8195577/
Abstract

INTRODUCTION

Platelet-rich plasma (PRP) is an increasingly used unconventional treatment option for erectile dysfunction (ED). The validity of PRP as a potential treatment for ED has been proposed in limited human trials. Furthermore, the costs associated with PRP for ED treatment are not readily promoted to patients. The goal of this review was to determine the efficacy and costs of PRP based on currently available literature and Canadian data.

METHODS

A comprehensive literature review of available PRP studies and current published data pertaining to cost, availability, and provider clinics globally was conducted using the PubMed database. Physicians offering genital PRP in Canada were identified using internet searches and PRP provider directories. Physician qualifications, clinic locations, and cost information were obtained from provider websites and telephone calls to identified clinics.

RESULTS

Availability of PRP injections offered for treating ED is increasing globally. There are currently no peer-reviewed publications to substantiate anecdotal evidence pertaining to the efficacy of PRP as a viable treatment option for ED patients. Our results indicate 19 providers for PRP injections in Canada, costing on average $1777 CAD per injection. No providers were affiliated with academic institutions and providers varied in their area of clinical speciality and training.

CONCLUSIONS

To our knowledge, there is currently no research underway investigating the clinical efficacy of PRP for ED treatment despite its broad availability and significant cost. Patients should be informed of the lack of substantiated efficacy and safety data, as the reliability of PRP treatments requires further evaluation.

摘要

引言

富血小板血浆(PRP)是一种越来越常用的治疗勃起功能障碍(ED)的非传统治疗方法。在有限的人体试验中提出了PRP作为ED潜在治疗方法的有效性。此外,与PRP治疗ED相关的费用并未轻易向患者宣传。本综述的目的是根据现有文献和加拿大数据确定PRP的疗效和成本。

方法

使用PubMed数据库对现有的PRP研究以及当前发表的有关全球成本、可及性和提供治疗的诊所的数据进行全面的文献综述。通过互联网搜索和PRP提供者目录确定在加拿大提供生殖器PRP治疗的医生。从提供者网站和致电已确定的诊所获取医生资质、诊所位置和成本信息。

结果

全球范围内提供用于治疗ED的PRP注射的可及性正在增加。目前尚无经过同行评审的出版物来证实有关PRP作为ED患者可行治疗选择的疗效的轶事证据。我们的结果表明,加拿大有19个PRP注射提供者,每次注射平均成本为1777加元。没有提供者隶属于学术机构,提供者在临床专业领域和培训方面各不相同。

结论

据我们所知,尽管PRP广泛可得且成本高昂,但目前尚无研究调查其治疗ED的临床疗效。应告知患者缺乏确凿的疗效和安全性数据,因为PRP治疗的可靠性需要进一步评估。