Division of Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.
Division of Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA; Department of Neurosurgery, Johns Hopkins University School of Medicine, 1800 Orleans Street, Baltimore, MD 21287, USA.
Neuroimaging Clin N Am. 2021 Feb;31(1):81-92. doi: 10.1016/j.nic.2020.09.004. Epub 2020 Nov 2.
Dynamic functional connectivity adds another dimension to resting-state functional MR imaging analysis. In recent years, dynamic functional connectivity has been increasingly used in resting-state functional MR imaging, and several studies have demonstrated that dynamic functional connectivity patterns correlate with different physiologic and pathologic brain states. In fact, evidence suggests that dynamic functional connectivity is a more sensitive marker than static functional connectivity; therefore, it might be a promising tool to add to clinical functional neuroimaging. This article provides a broad overview of dynamic functional connectivity and reviews its general principles, techniques, and potential clinical applications.
动态功能连接为静息态功能磁共振成像分析增加了另一个维度。近年来，动态功能连接在静息态功能磁共振成像中得到了越来越多的应用，多项研究表明，动态功能连接模式与不同的生理和病理脑状态相关。事实上，有证据表明，动态功能连接比静态功能连接更敏感；因此，它可能是一种很有前途的临床功能神经影像学工具。本文对动态功能连接进行了广泛的概述，回顾了其一般原理、技术和潜在的临床应用。
