心力衰竭中心脏磁共振结构-功能关系的定量评估。
Cardiac Magnetic Resonance Quantification of Structure-Function Relationships in Heart Failure.
机构信息
Division of Cardiology, David Geffen School of Medicine at UCLA, VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA; Diagnostic Cardiovascular Imaging Research Laboratory, Department of Radiology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; Physics & Biology in Medicine Graduate Program, University of California, Los Angeles, Los Angeles, CA, USA.
Diagnostic Cardiovascular Imaging Research Laboratory, Department of Radiology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; Physics & Biology in Medicine Graduate Program, University of California, Los Angeles, Los Angeles, CA, USA.
出版信息
Heart Fail Clin. 2021 Jan;17(1):9-24. doi: 10.1016/j.hfc.2020.08.001. Epub 2020 Oct 28.
Classification of heart failure is based on the left ventricular ejection fraction (EF): preserved EF, midrange EF, and reduced EF. There remains an unmet need for further heart failure phenotyping of ventricular structure-function relationships. Because of high spatiotemporal resolution, cardiac magnetic resonance (CMR) remains the reference modality for quantification of ventricular contractile function. The authors aim to highlight novel frameworks, including theranostic use of ferumoxytol, to enable more efficient evaluation of ventricular function in heart failure patients who are also frequently anemic, and to discuss emerging quantitative CMR approaches for evaluation of ventricular structure-function relationships in heart failure.
心力衰竭的分类基于左心室射血分数（EF）：射血分数保留、射血分数中间值和射血分数降低。对于进一步对心室结构-功能关系进行心力衰竭表型分型，仍存在未满足的需求。由于具有较高的时空分辨率，心脏磁共振（CMR）仍然是定量评估心室收缩功能的参考方式。作者旨在强调包括使用 Ferumoxytol 的治疗诊断用途在内的新框架，以更有效地评估同时伴有贫血的心力衰竭患者的心室功能，并讨论用于评估心力衰竭患者心室结构-功能关系的新兴定量 CMR 方法。
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