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[孕期绒毛膜促性腺激素的免疫测定。5种试剂的多中心研究]

[Immunological assay of chorionic gonadotropin during pregnancy. Multicenter study of 5 reagents].

作者信息

Patricot M C, Badonnel Y, Roger M, Revol A

机构信息

Laboratoire d'Hormonologie, Centre Hospitalier Lyon-Sud, Pierre Bénite.

出版信息

Ann Biol Clin (Paris). 1987;45(5):527-31.

PMID:3322114
Abstract

Five commercial kits for the quantitative determination of human chorionic gonadotropin (hCG) used for detection and monitoring of pregnancy were evaluated. Five kits used two-sites "sandwich" enzymoimmunoassay and monoclonal antibodies. Precision, standardization and sensitivity were tested and practicability was assessed. Good results are obtained for four kits (Beckman had poor results), sensitivity and specificity are good. Practicability of five kits was evaluated but choose was in relation to configuration of laboratory.

摘要

对用于妊娠检测和监测的五种定量检测人绒毛膜促性腺激素(hCG)的商业试剂盒进行了评估。五种试剂盒均采用双位点“夹心”酶免疫测定法和单克隆抗体。测试了精密度、标准化和灵敏度,并评估了实用性。四种试剂盒取得了良好结果(贝克曼试剂盒结果较差),灵敏度和特异性良好。评估了五种试剂盒的实用性,但具体选择取决于实验室配置。

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