Bahl Manisha
Department of Radiology, Massachusetts General Hospital/Harvard Medical School, 55 Fruit Street, WAC 240, Boston, MA 02114, USA.
Radiol Clin North Am. 2021 Jan;59(1):29-40. doi: 10.1016/j.rcl.2020.08.005.
High-risk breast lesions (HRLs) are a group of heterogeneous lesions that can be associated with a synchronous or adjacent breast cancer and that confer an elevated lifetime risk of breast cancer. Management of HRLs after core needle biopsy may include close imaging and clinical follow-up or excisional biopsy to evaluate for cancer. This article reviews histologic features and clinical presentation of each of the HRLs, current evidence with regard to management, and guidelines from the American Society of Breast Surgeons and National Comprehensive Cancer Network. In addition, imaging surveillance and risk-reduction strategies for women with HRLs are discussed.
高危乳腺病变（HRLs）是一组异质性病变，可能与同步或相邻的乳腺癌相关，且会增加乳腺癌的终生风险。在粗针活检后，HRLs的管理可能包括密切的影像学和临床随访，或进行切除活检以评估是否患有癌症。本文回顾了每种HRLs的组织学特征和临床表现、当前有关管理的证据，以及美国乳腺外科医生协会和国家综合癌症网络的指南。此外，还讨论了HRLs女性的影像学监测和风险降低策略。
