Crake T, Quyyumi A A, Wright C, Mockus L, Fox K M
National Heart Hospital, London.
Br Heart J. 1987 Dec;58(6):617-20. doi: 10.1136/hrt.58.6.617.
The relative efficacy of nifedipine and slow-release nifedipine (Adalat Retard) in the treatment of stable exertional angina pectoris was evaluated in a double blind randomised crossover study in eight patients on no concomitant antianginal treatment and in 10 patients who were additionally on atenolol. Patients were assessed by angina diaries and exercise testing. Slow-release nifedipine was as effective as nifedipine in the treatment of these patients, both alone and in combination with atenolol.
在一项双盲随机交叉研究中,对8例未接受其他抗心绞痛治疗的患者以及10例同时服用阿替洛尔的患者,评估了硝苯地平和缓释硝苯地平(拜新同缓释片)治疗稳定型劳力性心绞痛的相对疗效。通过心绞痛日记和运动试验对患者进行评估。缓释硝苯地平在单独使用以及与阿替洛尔联合使用时,治疗这些患者的效果与硝苯地平相当。