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艾司西酞普兰诱发严重静坐不能导致自杀未遂。

Escitalopram-induced severe akathisia leading to suicide attempt.

作者信息

Pratap Alok, Akhtar Sayeed, Sinha Prakriti, Bakhla Ajay Kumar

机构信息

Department of Psychiatry, Central Institute of Psychiatry, Ranchi, Jharkhand, India.

Former Deputy Medical superintendent, Central Institute of Psychiatry, Ranchi, Jharkhand, India.

出版信息

Ind Psychiatry J. 2019 Jul-Dec;28(2):315-317. doi: 10.4103/ipj.ipj_72_15. Epub 2020 Aug 14.

DOI:10.4103/ipj.ipj_72_15
PMID:33223729
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7660001/
Abstract

Akathisia, a distressing adverse reaction, is usually underdiagnosed or misdiagnosed in patients, who are treated with selective serotonin reuptake inhibitors (SSRIs). Escitalopram-induced akathisia is rarely reported in the literature. We report a case of severe akathisia leading to a suicide attempt in a 25-year-old male induced by 5 mg of escitalopram, that remitted completely after discontinuation of escitalopram and did not reappear later. Patient and their caretakers should be warned of symptoms of akathisia even when a very low dose of SSRI is prescribed.

摘要

静坐不能是一种令人痛苦的不良反应,在接受选择性5-羟色胺再摄取抑制剂(SSRI)治疗的患者中通常未得到充分诊断或被误诊。文献中很少报道艾司西酞普兰诱发的静坐不能。我们报告一例25岁男性因5毫克艾司西酞普兰诱发严重静坐不能并导致自杀未遂的病例,停用艾司西酞普兰后症状完全缓解,且后来未再出现。即使开具的是非常低剂量的SSRI,也应向患者及其护理人员警告静坐不能的症状。

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引用本文的文献

1
Escitalopram-induced akathisia in a patient with major depressive disorder: A rare case report.艾司西酞普兰致重度抑郁症患者静坐不能:一例罕见病例报告
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The Assessment and Treatment of Antipsychotic-Induced Akathisia.抗精神病药物所致静坐不能的评估与治疗
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The clinical challenges of akathisia.静坐不能的临床挑战。
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A case of akathisia induced by escitalopram: case report & review of literature.一例由艾司西酞普兰引起的静坐不能:病例报告及文献综述
Curr Drug Saf. 2014 Mar;9(1):56-9. doi: 10.2174/157488630901140224104651.
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Akathisia associated with carbamazepine therapy.与卡马西平治疗相关的静坐不能。
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