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富血小板血浆注射治疗颞部三角形脱发的短暂治疗反应:一例伴有皮肤镜检查随访的病例报告

Transient Treatment Response of Platelet-rich Plasma Injection for Temporal Triangular Alopecia: A Case Report with Dermoscopic Examination Follow-up.

作者信息

Lueangarun Suparuj, Pacharapakornpong Sarun, Tempark Therdpong

机构信息

Division of Dermatology, Chulabhorn International College of Medicine, Thammasat University, Amphur Klongluang, Pathumthani, Thailand.

Department of Pediatrics, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Pathumwan, Bangkok, Thailand.

出版信息

Int J Trichology. 2020 May-Jun;12(3):126-128. doi: 10.4103/ijt.ijt_52_20. Epub 2020 Aug 14.

Abstract

Temporal triangular alopecia (TTA) is congenital anomalies that usually develops in childhood, with rarely acquired cases in adults. TTA shares common clinical, dermoscopic, and histologic features of characterized vellus hair formation change, similar to androgenetic alopecia (AGA). Whereas, platelet-rich plasma (PRP) with multiple growth factors can provide treatment efficacy in AGA. Due to limited treatment for TTA, such as topical minoxidil, complete surgical excision, and hair transplantation, the multiple growth factors in PRP is thus postulated to be also effective for TTA treatment, just as in AGA. We present a case of TTA with unsatisfactory treatment outcome of only increased number and thickness of vellus hair by dermoscopic examination follow-up after the 5-session PRP injection and only transient response for 6 months. Unlike, AGA, the PRP injection might not consequently be a suitable treatment option for TTA. Nonetheless, further studies should be performed to investigate the potential treatment modality for TTA.

摘要

颞部三角形秃发(TTA)是一种先天性异常,通常在儿童期发病,成人中罕见后天获得性病例。TTA具有与特征性毳毛形成变化相关的常见临床、皮肤镜和组织学特征,类似于雄激素性秃发(AGA)。然而,富含多种生长因子的富血小板血浆(PRP)可对AGA提供治疗效果。由于TTA的治疗方法有限,如外用米诺地尔、完全手术切除和毛发移植,因此推测PRP中的多种生长因子对TTA治疗也同样有效,就像对AGA一样。我们报告了1例TTA患者,在接受5次PRP注射后,经皮肤镜检查随访,仅见毳毛数量和粗细增加,治疗效果不理想,且仅在6个月内有短暂反应。与AGA不同,PRP注射可能并非TTA的合适治疗选择。尽管如此,仍应进行进一步研究以探索TTA的潜在治疗方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03b7/7659735/94995a0b2ae5/IJT-12-126-g001.jpg

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