Chang Jinlong, Chu Yuyang, Ren Yandong, Li Chengchong, Wang Yuhua, Chu Xiang-Ping
Neuroscience Laboratory for Translational Medicine, School of Mental Health, Qiqihar Medical University Qiqihar 161006, China.
Feinberg School of Medicine, Northwestern University Chicago, Illinois 60611, USA.
Int J Physiol Pathophysiol Pharmacol. 2020 Oct 15;12(5):128-133. eCollection 2020.
A growing body of studies has demonstrated that acute transcranial magnetic stimulation (TMS) therapy for treatment-resistant major depressive disorder (MDD) has achieved significant antidepressant effects and can alleviate other related symptoms. However, MDD has a high relapse rate, and patients with depressive symptoms can relapse weeks or months after acute TMS treatment. The lack of necessary TMS maintenance protocols after completing acute TMS treatment with full remission might be one of the reasons for the high relapse rates in MDD patients. Thus, investigating post-TMS treatment maintenance guidelines is important for decreasing relapse in treatment-resistant depression patients who had initially responded to acute TMS therapy. Therefore, we recommend a scientific approach to decrease relapse in treatment-resistant depression patients who had initially responded to acute TMS treatment.
越来越多的研究表明，急性经颅磁刺激（TMS）疗法治疗难治性重度抑郁症（MDD）已取得显著的抗抑郁效果，并可缓解其他相关症状。然而，MDD的复发率很高，有抑郁症状的患者在急性TMS治疗数周或数月后可能会复发。在急性TMS治疗完全缓解后缺乏必要的TMS维持方案可能是MDD患者高复发率的原因之一。因此，研究TMS治疗后的维持指南对于降低最初对急性TMS治疗有反应的难治性抑郁症患者的复发率很重要。因此，我们推荐一种科学的方法来降低最初对急性TMS治疗有反应的难治性抑郁症患者的复发率。
