Emory University, Emory Spine Center, Atlanta, Georgia, USA.
Penn Medicine, Department of Rehab Medicine, USA.
Pain Med. 2021 Mar 18;22(3):561-566. doi: 10.1093/pm/pnaa341.
Prospectively evaluate the clinical outcomes of acute cervical radiculopathy with respect to soft disc herniations vs osteophytes.
Sixty consecutive patients who had had cervical radiculopathy for ≤1 month were enrolled in the study. Inclusion criteria were radicular pain greater than axial pain and a pain score ≥4 out of 10 on a numerical rating scale. Patients had at least one positive clinical finding: motor, sensory, or reflex changes. Plain films and magnetic resonance imaging were ordered. Follow-up was at 6 weeks and 3, 6, and 12 months. Outcomes included pain scores (neck and upper limb), neck disability index, medication use, opioid use, and need for surgery. Two attending musculoskeletal radiologists reviewed imaging findings for osteophytes vs soft disc herniations at the symptomatic level.
More than 75% reduction in pain was seen in 77% of patients with soft disc herniations and 66% of patients with osteophytes (P > 0.05) at 12 months. A pain score ≤2 out of 10 within 6 to 12 months was seen in 86% of patients with soft disc herniations and 81% of patients with osteophytes (P > 0.05). Moderate or marked improvement at 12 months was seen in 85% of patients with soft discs and 77% of patients with osteophytes (P > 0.05). Baseline-to-12-month numerical rating scale pain scores of patients with soft discs vs osteophytes had overlapping confidence intervals at each follow-up. At 12 months, very few had undergone surgery (7% of patients with soft discs, 11% of patients with osteophytes; P > 0.05) or were on opioids (7% of patients with soft discs, 9% of patients with osteophytes; P > 0.05).
The majority of patients, but not all patients, with acute radiculopathies improved with time. This was seen with both soft disc herniations and osteophytes.
前瞻性评估急性颈椎神经根病与软椎间盘突出症和骨赘的临床结果。
连续纳入 60 例颈椎神经根病患者,病程均≤1 个月。纳入标准为神经根痛重于轴性痛,数字评分量表疼痛评分≥4 分。患者至少有一项阳性临床发现:运动、感觉或反射改变。常规拍摄平片和磁共振成像。随访时间为 6 周及 3、6 和 12 个月。结果包括疼痛评分(颈部和上肢)、颈部残疾指数、药物使用、阿片类药物使用和手术需求。2 位主治的肌肉骨骼放射科医生对症状水平的骨赘和软椎间盘突出症的影像学表现进行了评估。
12 个月时,软椎间盘突出症患者中有 77%的疼痛缓解超过 75%,而骨赘患者中有 66%(P>0.05)。在 6 至 12 个月内,有 86%的软椎间盘突出症患者和 81%的骨赘患者疼痛评分≤2/10(P>0.05)。12 个月时,85%的软椎间盘患者和 77%的骨赘患者出现中度或明显改善(P>0.05)。软椎间盘和骨赘患者的基线至 12 个月数字评分量表疼痛评分在每个随访时间点的置信区间均有重叠。12 个月时,极少数患者(软椎间盘患者 7%,骨赘患者 11%;P>0.05)接受了手术,或使用阿片类药物(软椎间盘患者 7%,骨赘患者 9%;P>0.05)。
大多数(但不是所有)急性神经根病患者随着时间的推移而改善。这在软椎间盘突出症和骨赘中均可见。