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Comprehensive measures succeeded in improving early detection of leprosy cases in post-elimination era: Experience from Shandong province, China.综合措施成功提高消除后时代麻风病例的早期发现:来自中国山东省的经验。
PLoS Negl Trop Dis. 2020 Feb 20;14(2):e0007891. doi: 10.1371/journal.pntd.0007891. eCollection 2020 Feb.
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Point-of-Care Testing in Microbiology: A Mechanism for Improving Patient Outcomes.即时检测在微生物学中的应用:改善患者预后的一种手段。
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A portable device for nucleic acid quantification powered by sunlight, a flame or electricity.一种由阳光、火焰或电力驱动的便携式核酸定量设备。
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Rapid detection of Mycobacterium ulcerans with isothermal recombinase polymerase amplification assay.采用等温重组酶聚合酶扩增法快速检测溃疡分枝杆菌。
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9
Fingerstick test quantifying humoral and cellular biomarkers indicative for M. leprae infection.手指采血检测定量麻风杆菌感染所指示的体液和细胞生物标志物。
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资源有限环境下卡波西肉瘤和其他皮肤疾病的新型诊断方法。

Novel Diagnostics for Kaposi Sarcoma and Other Skin Diseases in Resource-Limited Settings.

机构信息

Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, 50 Staniford Street, Boston, MA 02114, USA.

Department of Dermatology, Massachusetts General Hospital, 50 Staniford Street, Boston, MA 02114, USA; University of Miami Miller School of Medicine, Miami, FL, USA.

出版信息

Dermatol Clin. 2021 Jan;39(1):83-90. doi: 10.1016/j.det.2020.08.008. Epub 2020 Oct 31.

DOI:10.1016/j.det.2020.08.008
PMID:33228864
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7845416/
Abstract

In resource-limited settings, point-of-care diagnostic devices have the potential to reduce diagnostic delays and improve epidemiologic surveillance of dermatologic conditions. We outline novel-point-of care diagnostics that have recently been developed for dermatologic conditions that primarily affect patients living in resource-limited settings, namely, Kaposi sarcoma, cutaneous leishmaniasis, leprosy, Buruli ulcer, yaws, onchocerciasis, and lymphatic filariasis. All of the technologies described in this article are prototypes, and some have undergone field testing. These devices still require validation in real-world settings and effective pricing to have a major impact on dermatologic care in resource-limited settings.

摘要

在资源有限的情况下,即时诊断设备有可能减少诊断延误,并改善对皮肤科疾病的流行病学监测。我们概述了最近为主要影响资源有限环境中患者的皮肤科疾病开发的新型即时诊断方法,即卡波济肉瘤、皮肤利什曼病、麻风病、布鲁里溃疡、雅司病、盘尾丝虫病和淋巴丝虫病。本文中描述的所有技术都是原型,有些已经经过现场测试。这些设备仍需要在实际环境中进行验证和有效的定价,才能对资源有限环境中的皮肤科护理产生重大影响。