Health Management Center, Health Management Research Center of Central South University, The Third Xiangya Hospital, Central South University, Hunan Province, China 410013.
Zhongguancun Xinzhiyuan Health Management Institute, Beijing, China 100011.
J Affect Disord. 2021 Feb 15;281:792-798. doi: 10.1016/j.jad.2020.11.060. Epub 2020 Nov 13.
This study aimed to investigate the cooccurrence of chronic pain (CP), depressive symptoms, and poor sleep quality in terms of prevalence and associated factors in a nationwide health check-up population in China.
This multicenter cross-sectional survey was performed in 2017. All the participants aged ≥18 years from eight health check-up institutions in 6 provinces and cities were invited to complete a self-report health questionnaire through online resources.
132,444 participants completed the online survey and the overall prevalence of CP and that of the three symptoms were 11.0% (95% confidence interval [95% CI]: 10.8-11.1) and 2.7% (95% CI: 2.6-2.8), respectively. The cooccurrence of all three symptoms increased with age, being higher in the female, widowed, unemployed, and lower education level groups. The respondents with multiple symptoms reported poorer self-rated health. Binary logistic regression analyses identified female sex (adjusted odds ratio [aOR]: 1.51; 95% CI: 1.42-1.62), a widowed status (aOR: 1.39; 95% CI: 1.04-1.84), a lower education level (aORs ranging from 1.46 to 2.47), and having one or more chronic diseases (aORs ranging from 1.43 to 2.02) to be significantly associated with reporting all three symptoms (all P ˂0.05). While long-term medication and regular exercise were the protective factors.
This study suggests that the cooccurrence of the three symptoms accounts for a certain proportion of the Chinese health check-up population. Integrated interventions that address CP and mental health cooccurrence may be an essential target for heath management in this population to tackle this considerable burden.
本研究旨在调查中国全国健康体检人群中慢性疼痛（CP）、抑郁症状和睡眠质量差的共病情况，包括其患病率和相关因素。
这是一项于 2017 年进行的多中心横断面研究。邀请来自 6 个省市 8 个体检机构年龄≥18 岁的所有参与者通过在线资源完成自我报告健康问卷。
132444 名参与者完成了在线调查，CP 的总体患病率和这三种症状的患病率分别为 11.0%（95%置信区间[95%CI]：10.8-11.1）和 2.7%（95%CI：2.6-2.8）。所有三种症状的共病发生率随年龄增长而增加，在女性、丧偶、失业和低教育程度人群中更高。报告多种症状的受访者自我报告的健康状况更差。二项逻辑回归分析确定女性（调整优势比[aOR]：1.51；95%CI：1.42-1.62）、丧偶（aOR：1.39；95%CI：1.04-1.84）、低教育程度（aOR 范围为 1.46-2.47）和患有一种或多种慢性病（aOR 范围为 1.43-2.02）与报告所有三种症状显著相关（均 P<0.05）。而长期用药和定期运动是保护因素。
本研究表明，这三种症状的共病在一定程度上存在于中国健康体检人群中。针对 CP 和精神健康共病的综合干预可能是该人群健康管理的一个重要目标，以应对这一相当大的负担。
