妊娠相关性高凝状态所致旁中央急性中渗
PARACENTRAL ACUTE MIDDLE MACULOPATHY ASSOCIATED WITH HYPERCOAGULABILITY IN PREGNANCY.
机构信息
Department of Ophthalmology, NYU School of Medicine, New York, New York.
出版信息
Retin Cases Brief Rep. 2023 Jan 1;17(1):29-32. doi: 10.1097/ICB.0000000000001093.
PURPOSE
To report a case of paracentral acute middle maculopathy in an otherwise healthy young, multiparous woman in her second trimester of pregnancy.
METHODS
A case report.
RESULTS
A 38-year-old woman in her twentieth week of pregnancy presented with a four-day history of an acute paracentral scotoma in her left eye. Fundoscopic examination of the left eye was significant for a white-gray lesion inferonasal to the fovea which corresponded with spectral-domain optical coherence tomography hyperreflectivity at the outer plexiform layer-inner nuclear layer junction and optical coherence tomography angiography nonperfusion. A diagnosis of paracentral acute middle maculopathy was made. The patient was sent for a hypercoagulability workup that revealed elevated Factor VIII activity, which has been associated with increased risk of complications during pregnancy.
CONCLUSION
Paracentral acute middle maculopathy in pregnancy may be secondary to an underlying hypercoagulable condition. We recommend systemic evaluation and referral to a high-risk pregnancy specialist if paracentral acute middle maculopathy is diagnosed during pregnancy. In addition, optical coherence tomography angiography in paracentral acute middle maculopathy may demonstrate reperfusion of the affected vessels.
目的
报告一例妊娠中期、健康年轻多产妇的旁中心急性中黄斑病变。
方法
病例报告。
结果
一名 38 岁的妇女在妊娠第二十周时出现左眼急性旁中心暗点，病史为四天。左眼眼底检查显示，在黄斑下鼻侧有一个灰白色病变，与频域光相干断层扫描在外丛状层-内核层交界处的高反射性和光相干断层扫描血管造影的无灌注相对应。诊断为旁中心急性中黄斑病变。患者进行了高凝状态检查，发现因子 VIII 活性升高，这与妊娠期间并发症风险增加有关。
结论
妊娠中旁中心急性中黄斑病变可能继发于潜在的高凝状态。如果在妊娠期间诊断出旁中心急性中黄斑病变，我们建议进行全身评估并转介给高危妊娠专家。此外，旁中心急性中黄斑病变的光相干断层扫描血管造影可能显示受累血管再灌注。
Zotero 插件