Wolk B H
Can Med Assoc J. 1977 Oct 8;117(7):750-3.
Between 1934 and 1975, 16 patients with primary malignant lymphoma cutis were seen at the Ottawa clinic of the Ontario Cancer Foundation. The lesions were purplish, firm, dermal or hypodermal (or both) nodules, tumours and plaques. In all 16 the histopathologic diagnosis was diffuse non-Hodgkin's lymphoma; 12 were considered to have prognostically bad lymphomas. However, the prognosis of primary malignant lymphoma cutis is significantly more favourable than is implied by the stage IV designation that such localized extranodal involvement would have required under the Rye clinical staging classification.
1934年至1975年间,安大略癌症基金会渥太华诊所共接诊了16例原发性皮肤恶性淋巴瘤患者。皮损表现为紫色、质地坚实的真皮或皮下(或两者皆有)结节、肿瘤及斑块。所有16例患者的组织病理学诊断均为弥漫性非霍奇金淋巴瘤;其中12例被认为是预后不良的淋巴瘤。然而,原发性皮肤恶性淋巴瘤的预后明显优于根据Rye临床分期分类中这种局限性结外受累所需要的IV期指定所暗示的预后。