Geerts M L, Busschots A M
Department of Dermatology, University Hospital Ghent, Belgium.
Dermatol Clin. 1994 Apr;12(2):409-17.
The skin lesions of two elderly women lead us to the diagnosis of small cleaved lymphocytic B-cell non-Hodgkin's lymphoma, TNM stage IVb after clinical staging examinations. Relapses occurred within less than 1 year. Morphology, enzymhistochemistry (alkaline phosphatase in the first case), and immunohistochemistry (CD 5 positivity in the second case) in the skin biopsies supported the diagnosis of mantle-cell lymphoma. The histogenesis of the mantle-cell lymphoma is reviewed.
两名老年女性的皮肤病变经临床分期检查后,我们诊断为小裂细胞性B细胞非霍奇金淋巴瘤,TNM分期为IVb期。不到1年内就出现了复发。皮肤活检中的形态学、酶组织化学(第一例为碱性磷酸酶)和免疫组织化学(第二例为CD 5阳性)支持套细胞淋巴瘤的诊断。本文对套细胞淋巴瘤的组织发生进行了综述。