Department of Plastic Surgery, Medical College of Wisconsin, Milwaukee, WI, USA.
Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
J Plast Reconstr Aesthet Surg. 2022 May;75(5):1551-1556. doi: 10.1016/j.bjps.2021.11.077. Epub 2021 Nov 29.
This study aimed to understand the current utilization of surgical approaches for nerve ending management in upper extremity amputation to prevent and treat nerve-related pain. We administered a survey to 190 of 1270 surgeons contacted by email (15% response rate) and analyzed their demographics, practice patterns, and perceptions regarding techniques for nerve ending management in upper extremity amputees. Although many surgical techniques were employed, most surgeons (54%) performed traction neurectomy during amputation and, alternatively, bury nerve into muscle if a neuroma subsequently develops (52%). Surgeons in practice less than 10 years were more likely to perform targeted muscle reinnervation (TMR) and regenerative peripheral nerve interfaces (RPNI) than surgeons in practice greater than 10 years (p<0.001). TMR and RPNI were performed more frequently for proximal amputations than distal amputations, but there is no consensus regarding the optimal timing to utilize these techniques. Surgeons commonly cited improved prosthetic control, pain, and phantom limb symptoms as reasons for performing TMR and RPNI. Increased physician compensation as a consideration was more commonly cited among TMR non-adopter than adopters (31% vs 14%, p=0.008). There is no consensus regarding techniques for the prevention or treatment of nerve ending pain in upper extremity amputees. TMR and RPNI are being utilized with increasing frequency and both patient and surgeon factors affect implementation in clinical practice.
本研究旨在了解上肢截肢中用于处理神经末梢以预防和治疗神经相关疼痛的手术方法的当前应用情况。我们向通过电子邮件联系的 1270 名外科医生中的 190 名(15%的回复率)发送了一份调查,并分析了他们的人口统计学、实践模式以及对上肢截肢患者神经末梢处理技术的看法。尽管采用了许多手术技术,但大多数外科医生(54%)在截肢时进行牵引神经切除术,如果随后出现神经瘤,则将神经埋入肌肉(52%)。实践经验不足 10 年的外科医生比实践经验超过 10 年的外科医生更有可能进行靶向肌肉神经再支配(TMR)和再生周围神经接口(RPNI)(p<0.001)。TMR 和 RPNI 更常用于近端截肢,而不是远端截肢,但对于这些技术的最佳应用时机尚无共识。外科医生通常将改善假肢控制、疼痛和幻肢症状作为进行 TMR 和 RPNI 的原因。考虑增加医生报酬的情况在 TMR 非使用者中比使用者中更为常见(31%比 14%,p=0.008)。对于上肢截肢患者神经末梢疼痛的预防或治疗方法,目前尚无共识。TMR 和 RPNI 的应用频率越来越高,患者和外科医生的因素都会影响其在临床实践中的实施。