Department of Psychiatry and Psychotherapy, Berlin Institute of Health, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, Campus Charité Mitte, Berlin, Germany.
Division of Adult Psychiatry, Department of Psychiatry, Geneva University Hospitals, 2, Chemin du Petit-Bel-Air, 1226, Thonex, Switzerland.
Eur Arch Psychiatry Clin Neurosci. 2021 Sep;271(6):1077-1087. doi: 10.1007/s00406-020-01215-x. Epub 2020 Nov 24.
Post-coercion review is increasingly regarded as a mean to reduce the negative consequences of coercive interventions, including the development of posttraumatic symptoms. However, the efficacy of this intervention in preventing posttraumatic symptoms or PTSD has not been sufficiently studied. The objective of this study is to examine the influence of a single, standardized post-coercion review session on the development or exacerbation of PTSD symptoms in patients with psychotic disorders.
In a multi-center, two-armed, randomized controlled trial, patients who experienced coercive interventions during current hospitalization were either randomized to standard treatment or an intervention group receiving a guideline-based, standardized reflecting review session. Factorial MANCOVA and subsequent ANCOVAs investigated the effects of the post-coercion reflecting review session on post-traumatic symptoms as measured by the subscales of the Impact of Events Scale-Revised (IES-R). Similarly, the effect of the intervention on the intensity of the peritraumatic reactions measured by the Peritraumatic Distress Inventory (PDI) was analyzed by conducting a factorial ANCOVA.
N = 82 patients were included in an intention-to-treat analysis. MANCOVA and post hoc ANCOVAs revealed a significant main effect of the intervention for the IES-R subscales intrusion and hyperarousal, when controlling for levels of peritraumatic distress, whereby intervention group participants presented lower respective mean scores. There was no significant difference regarding the intensity of the peritraumatic reaction.
Standardized post-coercion review contributes to a reduction of the burden of PTSD symptoms in patients with psychotic disorders experiencing coercive interventions in acute settings and shall be recommended as a measure of trauma-informed care. The trial was registered at ClinicalTrials.gov (ID NCT03512925) on 01/30/2018 (retrospectively registered).
强制干预后审查越来越被视为减少强制性干预负面后果的手段,包括创伤后症状的发展。然而,这种干预预防创伤后症状或 PTSD 的效果尚未得到充分研究。本研究的目的是检验单次标准化强制干预后审查对精神障碍患者 PTSD 症状发展或恶化的影响。
在一项多中心、双臂、随机对照试验中,在当前住院期间经历过强制性干预的患者被随机分配到标准治疗组或干预组,接受基于指南的标准化反思性审查。因子 MANCOVA 和随后的 ANCOVA 调查了强制干预后反思性审查对创伤后症状的影响,使用修订后的事件影响量表(IES-R)的子量表进行测量。同样,通过进行因子 ANCOVA 分析,评估干预对创伤前应激障碍量表(PDI)测量的创伤前反应强度的影响。
共有 82 名患者纳入意向治疗分析。MANCOVA 和事后 ANCOVA 显示,在控制创伤前应激水平的情况下,干预对 IES-R 子量表入侵和警觉性增高有显著的主效应,干预组参与者的相应平均得分较低。创伤前反应强度没有显著差异。
标准化强制干预后审查有助于减少急性环境中经历强制性干预的精神障碍患者 PTSD 症状的负担,应作为创伤知情护理的措施予以推荐。该试验于 2018 年 1 月 30 日(回溯注册)在 ClinicalTrials.gov(注册号 NCT03512925)注册。