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建筑工人中长期阿片类药物使用和阿片类药物使用障碍的预测因素:索赔数据分析。

Predictors of long-term opioid use and opioid use disorder among construction workers: Analysis of claims data.

机构信息

Division of General Medical Sciences, Washington University School of Medicine, St. Louis, Missouri, USA.

出版信息

Am J Ind Med. 2021 Jan;64(1):48-57. doi: 10.1002/ajim.23202. Epub 2020 Nov 24.

Abstract

BACKGROUND

Construction workers have high rates of work-related musculoskeletal disorders, which lead to frequent opioid use and opioid use disorder (OUD). This paper quantified the incidence of opioid use and OUD among construction workers with and without musculoskeletal disorders.

METHODS

We conducted a retrospective study using union health claims from January 2015 to June 2018 from 19,909 construction workers. Claims for diagnoses of chronic musculoskeletal disorders, acute musculoskeletal injuries, musculoskeletal surgery, and other conditions were linked to new opioid prescriptions. We examined the effects of high doses (≥50 morphine mg equivalents per day), large supply (more than 7 days per fill), long-term opioid use (60 or more days supplied within a calendar quarter), and musculoskeletal disorders, on the odds of a future OUD.

RESULTS

There were high rates (42.8% per year) of chronic musculoskeletal disorders among workers, of whom 24.1% received new opioid prescriptions and 6.3% received long-term opioid prescriptions per year. Workers receiving opioids for chronic musculoskeletal disorders had the highest odds of future OUD: 4.71 (95% confidence interval 3.09-7.37); workers prescribed long-term opioids in any calendar quarter had a nearly 10-fold odds of developing an OUD.

CONCLUSIONS

Among construction workers, opioids initiated for musculoskeletal pain were strongly associated with incident long-term opioid use and OUD. Musculoskeletal pain from physically demanding work is likely one driver of the opioid epidemic in occupations like construction. Prevention of work injuries and alternative pain management are needed for workers at risk for musculoskeletal injuries.

摘要

背景

建筑工人的工作相关肌肉骨骼疾病发生率较高,这导致他们频繁使用阿片类药物,并出现阿片类药物使用障碍(OUD)。本文量化了患有和不患有肌肉骨骼疾病的建筑工人中阿片类药物使用和 OUD 的发生率。

方法

我们使用了 19909 名建筑工人从 2015 年 1 月至 2018 年 6 月的工会健康索赔数据进行回顾性研究。将慢性肌肉骨骼疾病、急性肌肉骨骼损伤、肌肉骨骼手术和其他疾病的诊断索赔与新的阿片类药物处方相关联。我们研究了高剂量(≥50 吗啡毫克当量/天)、大供应量(每次配药超过 7 天)、长期阿片类药物使用(在一个日历季度内供应 60 天或以上)以及肌肉骨骼疾病对未来 OUD 发生的几率的影响。

结果

工人中慢性肌肉骨骼疾病的发生率较高(每年 42.8%),其中 24.1%的人获得了新的阿片类药物处方,每年有 6.3%的人获得了长期阿片类药物处方。接受阿片类药物治疗慢性肌肉骨骼疾病的工人发生未来 OUD 的几率最高:4.71(95%置信区间 3.09-7.37);在任何一个日历季度接受长期阿片类药物处方的工人,发生 OUD 的几率几乎增加了 10 倍。

结论

在建筑工人中,为肌肉骨骼疼痛开的阿片类药物与长期阿片类药物使用和 OUD 的发生有很强的相关性。体力劳动引起的肌肉骨骼疼痛可能是建筑等职业阿片类药物流行的一个驱动因素。需要预防工人受伤和替代疼痛管理,以减少肌肉骨骼受伤的风险。

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