Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.
School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.
Lymphat Res Biol. 2021 Jun;19(3):206-214. doi: 10.1089/lrb.2020.0085. Epub 2020 Nov 25.
Bioelectrical impedance spectroscopy (BIS) is a technology that is widely used for the assessment of body composition. The method is based on the measurement of the electrical resistance of the body or a body region that can be quantitatively related to the amount of water in the tissues. Lymphedema is characterized, at least in its early stages, as an accumulation of lymph, an extracellular fluid. In the late 1980s, it was recognized that it might be possible to adapt BIS protocols to measure this increase in lymph volume. Subsequently, the use of BIS for the early detection of breast cancer-related lymphedema was demonstrated in the early 1990s, with BIS reference values indicative of lymphedema published in 2001. The subsequent two decades have seen BIS become a widely accepted method for lymphedema assessment. This review traces the evolution of the BIS technique since its inception and presents the current state of the art, with particular emphasis on utility in clinical practice.
生物电阻抗谱（BIS）是一种广泛用于评估身体成分的技术。该方法基于对身体或身体部位的电阻测量，该测量可定量反映组织中的水量。淋巴水肿至少在其早期阶段表现为淋巴液（细胞外液）的积聚。在 20 世纪 80 年代后期，人们认识到可能会适应 BIS 协议来测量这种淋巴体积的增加。随后，在 20 世纪 90 年代早期证明了 BIS 可用于早期检测乳腺癌相关的淋巴水肿，2001 年发表了提示淋巴水肿的 BIS 参考值。随后的二十年中，BIS 已成为一种广泛接受的淋巴水肿评估方法。本综述追溯了自 BIS 技术问世以来的发展历程，并展示了当前的最新技术，特别强调了其在临床实践中的应用。
