Mackenzie Charles D, Kapa D Ramaiah, Krishnasastry Suma, Douglass Jan, Hoerauf Achim, Ottesen Eric A
Coalition for Operational Research on Neglected Tropical Diseases (COR-NTD), Task Force for Global Health, Atlanta, Georgia.
The END Fund, New York, New York.
Am J Trop Med Hyg. 2024 Jul 30;111(4_Suppl):3-21. doi: 10.4269/ajtmh.23-0905. Print 2024 Oct 1.
Providing and improving the care of patients suffering from lymphedema remains an essential goal for the clinical management of populations affected by lymphatic filariasis. Although the Essential Package of Care (EPC) recommended by the WHO leads to important positive benefits for many of these lymphedema patients, it is important to continue to address the challenges that remain both in quantifying these effects and in ensuring optimal care. This report, based on the authors' scientific and field experience, focuses on the impact and significance of lymphedema, its clinical presentation, current treatment approaches, and the importance of lymphedema care to the Global Program to Eliminate Lymphatic Filariasis. It emphasizes specific practical issues related to managing lymphedema, such as the importance of beginning treatment in the condition's early stages and the development of effective approaches to assess patients' progress toward improving both their clinical status and their overall quality of life. Priorities for research are also examined, particularly the need for tools to identify patients and to assess disease burden in endemic communities, the creation of EPC accessibility to as many patients as possible (i.e., targeting 100% "geographic coverage" of care), and the empowerment of patients to ensure the sustainability, and ultimately the provision of care from sectors of the national public health systems of endemic countries.
为淋巴水肿患者提供并改善护理仍然是淋巴丝虫病流行地区临床管理的一项重要目标。虽然世界卫生组织推荐的基本护理包(EPC)给许多淋巴水肿患者带来了重要的积极益处,但继续应对在量化这些效果以及确保最佳护理方面仍然存在的挑战很重要。本报告基于作者的科学和实地经验,重点关注淋巴水肿的影响和重要性、其临床表现、当前的治疗方法以及淋巴水肿护理对全球消除淋巴丝虫病规划的重要性。它强调了与管理淋巴水肿相关的具体实际问题,例如在病情早期开始治疗的重要性以及制定有效的方法来评估患者在改善临床状况和整体生活质量方面的进展。还探讨了研究重点,特别是需要用于识别患者和评估流行社区疾病负担的工具,使尽可能多的患者能够获得基本护理包(即实现护理的100%“地理覆盖”),以及增强患者能力以确保护理的可持续性,并最终由流行国家的国家公共卫生系统部门提供护理。