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用于生物产品分离的多孔膜电渗析:技术、特点与进展

Electrodialysis with porous membrane for bioproduct separation: Technology, features, and progress.

作者信息

Sun Luqin, Chen Qingbai, Lu Huixia, Wang Jianyou, Zhao Jinli, Li Pengfei

机构信息

Tianjin Key Laboratory of Environmental Technology for Complex Trans-Media Pollution, College of Environmental Science and Engineering, Nankai University, Tianjin 300350, China.

Tianjin Key Laboratory of Environmental Technology for Complex Trans-Media Pollution, College of Environmental Science and Engineering, Nankai University, Tianjin 300350, China.

出版信息

Food Res Int. 2020 Nov;137:109343. doi: 10.1016/j.foodres.2020.109343. Epub 2020 Jun 10.

DOI:10.1016/j.foodres.2020.109343
PMID:33233052
Abstract

Electrodialysis with porous membrane (EDPM) is a recently developed membrane separation process, in which one or more porous filtration membranes stacked in an electrodialysis cell. It is a promising technology for separation, purification or concentration of bioactive components for it associates the excellent properties of electrodialysis (ED), porous filtration membrane, and electrophoresis. There are a number of studies having attempted to optimize the performance of EDPM processing, however, it still has some limitations involving low productivity with one pair of separation unit, membrane fouling and few applications on the fractionation of components with high molecular weight. This paper offers a comprehensive overview of recent studies devoted to EDPM, including principles, configurations, mathematical model regarding mass transfer, process performance optimization, membrane fouling and applications in as much detail as possible. In addition, a collection of other separation technologies based on electrophoresis at a preparative scale are presented to illustrate their limitations on the large-scale application. Some drawbacks of EDPM have been put forward. To achieve full scale applications of EDPM, there are still many issues to overcome. Finally, an outlook for prospective development of EDPM technology is given.

摘要

多孔膜电渗析(EDPM)是一种最近开发的膜分离工艺,其中一个或多个多孔过滤膜堆叠在一个电渗析池中。它是一种用于生物活性成分分离、纯化或浓缩的有前途的技术,因为它结合了电渗析(ED)、多孔过滤膜和电泳的优异特性。有许多研究试图优化EDPM工艺的性能,然而,它仍然存在一些局限性,包括一对分离单元的生产率低、膜污染以及在高分子量成分分馏方面的应用较少。本文全面概述了最近关于EDPM的研究,包括原理、配置、传质数学模型、工艺性能优化、膜污染以及尽可能详细的应用。此外,还介绍了一系列基于制备规模电泳的其他分离技术,以说明它们在大规模应用中的局限性。提出了EDPM的一些缺点。为了实现EDPM的全面应用,仍有许多问题需要克服。最后,给出了EDPM技术的未来发展展望。

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