From the Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital.
Plast Reconstr Surg. 2020 Dec;146(6):731e-736e. doi: 10.1097/PRS.0000000000007384.
Breast reconstruction is most frequently performed using implants or expanders. Adjunctive materials such as acellular dermal matrix and synthetic meshes are used to support the implant or expander. A paucity of large studies exist on the use of synthetic mesh for breast reconstruction.
A retrospective chart review of all patients over the past 7 years who had implant reconstruction with synthetic absorbable mesh at the Massachusetts General Hospital was performed. Data were collected on demographic and surgical outcomes. Statistical analysis was performed.
A total of 227 patients (376 mastectomies) were treated with direct-to-implant subpectoral reconstruction with absorbable mesh from 2011 to 2017. The infection rate was 2.1 percent. The rate of capsular contracture was 4.8 percent. Patients who had radiation therapy either preoperatively or postoperatively had a higher rate of complications, including capsular contracture. Cost savings for using mesh instead of acellular dermal matrix surpassed $1.2 million.
Synthetic absorbable mesh is a safe alternative to acellular dermal matrix in prosthetic breast reconstruction and provides stable results along with significant cost savings.
CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.
乳房重建最常使用植入物或扩张器进行。诸如脱细胞真皮基质和合成网片等辅助材料用于支撑植入物或扩张器。用于乳房重建的合成网片的大量大型研究尚不多见。
对过去 7 年在马萨诸塞州综合医院接受过合成可吸收网片植入物重建的所有患者进行了回顾性图表审查。收集了人口统计学和手术结果的数据。进行了统计分析。
2011 年至 2017 年间,共有 227 名患者(376 例乳房切除术)接受了直接到植入物下胸肌重建的可吸收网片治疗。感染率为 2.1%。包膜挛缩率为 4.8%。接受术前或术后放疗的患者并发症发生率更高,包括包膜挛缩。使用网片而不是脱细胞真皮基质可节省超过 120 万美元的成本。
在假体乳房重建中,合成可吸收网片是脱细胞真皮基质的安全替代品,可提供稳定的结果并显著节省成本。
临床问题/证据水平:治疗,IV。